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Pycnogenol +

product on market Capsule Wonder Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Pycnogenol and grape seed extract provide antioxidant support with moderate evidence for improving circulation and vascular health. Vitamin C and rutin further support connective tissue and capillary integrity. Overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Pycnogenol +
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
50 mg (83.3% DV)
Pycnogenol
30 mg
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
5 mg
Market median: 500.0mg (19 products)

Other Ingredients

Vegetable Cellulose Gelatin Calcium Carbonate Magnesium Carbonate Vegetable Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: One to three capsules daily.

Warnings & Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Keep out of reach of children.

Formulation Notes

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Pycnogenol is a natural plant extract made from the bark of the European coastal pine, Pinus Maritima, growing along the coast of southern France - from Bordeaux to the Spanish border.

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Pycnogenol French Maritime Pine Bark Extract

Pycnogenol + Plus Vitamin C Grape seed and Rutin

Gluten free

Promotes healthy circulation

Additional Information

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees - 30 degrees C).

Made in USA

Formula 663

Metadata

Product Details

UPC / SKU0 99528 66360 6
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormCapsule
DSLD ID215578
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.