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Folic Acid 400 mcg

product on market Tablet or Pill Mason Natural Safety: 60/100
60/100

Review before taking

  • Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Folate is supported by strong evidence for preventing neural tube defects during pregnancy and supporting cellular growth. However, the low evidence coverage and safety score suggest a need for caution. Potential concerns may exist regarding dosage or purity for certain users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of folate exceeds the recommended daily upper limit. Taking more than this limit may be unsafe.

Label

Product Label

Label for Folic Acid 400 mcg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

665 mcg DFE (166% DV)
Exceeds UL by 665.0× (UL: 1.0 mg) 226 studies (A:10, B:105)

Other Ingredients

Whey Microcrystalline Cellulose Calcium Carbonate Croscarmellose Sodium Stearic Acid Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults - Take one tablet daily, preferably with food, as a dietary supplement.

Warnings & Precautions

Allergen certification - This product contains milk derivatives (Whey).

Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Tamper-evident seal: Do not use product if seal appears tampered.

Formulation Notes

May support cardiovascular health & women of childbearing age

Guaranteed no added: Starch, yeast, soy, corn, wheat, egg, fragrance, artificial colors or flavors and preservatives. Sodium free.

Soy free

Additional Information

Mason Guarantee Laboratory Tested cGMP Certified Good Manufacturing Practice Certified

N Mason Natural Est. 1967

DFE - Dietary Folate equivalents

Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).

Metadata

Product Details

UPC / SKU3 11845 06531 5
DSLD Entry Date2020-02-26
Product TypeVitamin
FormTablet or Pill
BrandMason Natural
DSLD ID214529
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
View all evidence for Folate →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.