🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Botanical Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Pycnogenol Pine bark extract
15 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 35mg

Other Ingredients

Cellulose Calcium Carbonate Stearic Acid Magnesium Stearate

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (85% of products) Nutrient (9% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

RECOMMENDATION: One (1) tablet one (1) to two (2) times each day as a dietary supplement or as otherwise directed by a healthcare professional.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN

Additional Information

Rev. 8/08

Lot Number: Exp. Date:

Store in a cool, dry area.

Sealed with an imprinted safety seal for your protection.

Product Details

DSLD Entry Date 2013-06-25
Product Type Botanical
Form Tablet or Pill
DSLD ID 21436
Data Updated 2026-04-11

Research Evidence

14 Research Sources
50 Avg Quality Score
9 Rct
2 Meta Analysis
2 Clinical Trial
1 Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies
View all evidence for Grape Seed →

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