🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

100 mcg (143% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
📊 Market median: 80.0mg (20 products) 📚 334 studies (Tier A: 8, B: 183)
This product: 60mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 250mg
N-Acetyl-Cysteine
200 mg
50 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 50mg

Other Ingredients

Acacia fiber Hypromellose non-GMO Rice hull concentrate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (79% of products) Nutrient (50% of products) Qualified Health (5% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 2 capsules daily or as directed by a healthcare professional. May be taken with meals or on an empty stomach. For best results maintain a balanced diet and healthy lifestyle. Consult your primary healthcare provider about the use of any dietary supplements. For optimal digestive health, pair this product with Dr. Ohhira's Probiotics Original Formula. See box insert for complete instructions. Potency through date on box when stored as directed.

⚠️ Warnings & Precautions

As with all dietary supplements, keep out of the reach of children.

Do not purchase if safety seal is broken.

🧪 Formulation Notes

Glutathione-producing Lactobacillus fermentum ME-3

Revolutionary antioxidant and liver health support Supports healthy detoxification and normal liver function

Plus: Milk thistle fruit extract (200 mg Silymarin), L-selenomethionine

Reg'Activ Detox & Liver Health contains the revolutionary probiotic strain Lactobacillus fermentrum ME-3. Studied for over 20 years, ME-3 produces the super antioxidant glutathione, which supports liver tissue health and function on a cellular level. Most detox herbals work by promoting healthy glutathione levels and activity. L-Methionine and N-Acetyl-cysteine (NAC) are glutathione precursors. L-selenomethionine promotes healthy levels of glutathione peroxidase. Milk thistle supports super antioxidant enzymes in the liver. Reg Activ harnesses the synergy of these ingredients and pairs it with powerful Lactobacillus fermentum ME-3.

Product does not contain milk, egg, fish, crustacean shellfish, tree nuts, wheat (gluten), peanuts or soybeans.

20 Years of Published Research: Probiotic research is transforming human health; Reg'Activ products build upon these breakthroughs. In 1995, award-winning microbiologist Marika Mikelsaar, MD, PhD and her team of research scientists isolated a unique probiotic strain, Lactobacillus fermentum ME-3. ME-3 produces glutathione, which acts as the Master Antioxidant in every human cell. Glutathione is a key regulator of detoxification throughout the body, with highest concentrations found in the liver.

Additional Information

Certified Vegan AVA American Vegetarian Association

Store at room temperature 59 degrees - 77 degrees F (15 degrees - 25 degrees C). Protect from direct sunlight and humidity. No refrigeration required.

Product of the Netherlands.

Product Details

UPC / SKU 6 95927 22203 3
DSLD Entry Date 2020-02-26
Product Type Other Combinations
Form Capsule
Brand Reg'Activ
DSLD ID 211563
Data Updated 2026-04-11

Research Evidence

273 Research Sources
55 Avg Quality Score
131 Meta Analysis
61 Systematic Review
55 Rct
19 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Other
1 Observational
1 Openfda Safety
A Selenium for preventing cancer
Meta Analysis The Cochrane database of systematic reviews 2018
A Selenium supplementation for the primary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2013
A Selenium supplementation for critically ill adults
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011
B Selenium and prostate cancer: systematic review and meta-analysis
Meta Analysis The American journal of clinical nutrition 2012
B Selenium supplementation for Hashimoto's thyroiditis
Systematic Review The Cochrane database of systematic reviews 2013
B Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy
Meta Analysis The Cochrane database of systematic reviews 2017
B Selenium, antioxidants, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis The American journal of clinical nutrition 2020
B The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2017
B Meta-analysis of selenium effects on the meat quality of broilers
Meta Analysis Poultry science 2024
View all evidence for Selenium →

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