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Skin and Joints Essentials

product on market Softgel Capsule Perricone MD Nutriceuticals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines Vitamin E with omega-6 and omega-3 fatty acids from evening primrose, borage, black currant, and flaxseed oils. Research provides moderate evidence that these ingredients support skin barrier function and joint health by reducing inflammation. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Skin and Joints Essentials
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Botanical with Nutrients
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

7.5 IU (25% DV)
Within RDA (0.3× RDA) 179 studies (A:3, B:90)
Oil of Evening Primrose
166 mg
Oil of Borage
166 mg
Black Currant seed Oil
166 mg
333 mg
Market median: 1000.0mg (212 products) 12 studies (A:0, B:3)
Rosemary extract
2.5 mg

Other Ingredients

Gelatin Glycerin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions Dr. Perricone recommends taking one packet twice daily with meals. A 30-day program.

Warnings & Precautions

Warning: Before using any dietary supplement, pregnant or lactating women should consult with a physician or health professional.

Keep out of the reach of children.

To preserve quality and freshness, store in a cool, dry place at controlled room temperature 15(0)-30(0)C Tamper evident: Do not use if packet is cut, torn, or broken.

Formulation Notes

Nourishes the body and the skin.

Product Benefits Targeted nutritional supplements are an essential part of Dr. Perricone's 3-Tier philosophy to healthy aging and beautiful skin. This daily program of nutrients is especially designed to support the health of skin. It also supports bone and joint function and healthy hair and nails.

Free of sugar, preservatives, yeast, artificial colors-flavors-dyes.

Additional Information

Each packet contains: 3 softgels, 2 capsules and 3 caplets.

Clinical studies In a 8 week study, 86% reported improved skin texture. 78% reported healthier skin appearance. 65% reported lessening of crow's feet & lines and wrinkles.

Decades of research Perricone MD products are unique in that they are patented, researched and formulated by Nicholas Perricone, M.D., board certified dermatologist and anti-aging expert.

To preserve quality and freshness, store in a cool, dry place at controlled room temperature 15(0)-30(0)C Tamper evident: Do not use if packet is cut, torn, or broken.

This carton is fully recyclable. It's manufactured using wind power and printed in a carbon neutral facility.

Made in USA.

C6 Carbon neutral

Metadata

Product Details

DSLD Entry Date2019-12-22
Product TypeBotanical with Nutrients
FormSoftgel Capsule
DSLD ID209920
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.