Home/ Supplements/ Niacin/ Niacin 500 mg

Niacin 500 mg

product on market Tablet or Pill Carlson Safety: 80/100
80/100

This product is generally safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Niacin is used to support cholesterol levels and cardiovascular health, with strong evidence supporting its efficacy. Calcium is essential for bone density and nerve function. Due to the very low evidence coverage for this specific formulation, the overall clinical data for this product profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Niacin 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
100
Servings
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
Calcium
26 mg (2% DV)

Other Ingredients

Microcrystalline Cellulose Stearic Acid Magnesium Stearate Ethylcellulose Croscarmellose Sodium Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults: Take one tablet daily at mealtime.

Warnings & Precautions

Note: Niacin may cause a warm flushing of the skin which may last minutes or hours and can often be relieved by drinking 1 or 2 glasses of water.

Warning: Do not take if you are pregnant or lactating.

Do not take if you have low blood pressure without first consulting your physician.

Formulation Notes

Heart function Energy production Healthy lipids

The tablets are prepared to disintegrate over a period of up to two hours under simulated physiological conditions.

Niacin (vitamin B-3) is an essential B vitamin that's important for properly metabolizing fat and fat-like substances. Niacin supports healthy cardiovascular function and energy production.

Gluten-free No artificial preservatives

Additional Information

An FDA Regulated Facility

Potency & quality guaranteed

Metadata

Product Details

UPC / SKU0 88395 02781 9
DSLD Entry Date2019-11-21
Product TypeSingle Vitamin and Mineral
FormTablet or Pill
BrandCarlson
DSLD ID209249
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
Compare

Similar Products

View all Niacin products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.