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OptygenHP

product on market Capsule First Endurance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Beta-alanine has strong evidence for buffering muscle acidity, while rhodiola and ashwagandha show moderate support for reducing fatigue and stress. Cordyceps and chromium are included for energy and metabolic support, though evidence for these is more limited. The ingredient profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for OptygenHP
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

200 mcg (167% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)
Market median: 300.0mg (122 products) 22 studies (A:0, B:7)
Cordyceps
800 mg
1500 mg
Market median: 1500.0mg (104 products) 21 studies (A:0, B:2)
ActiGin Proprietary Matrix
50 mg
ATPro Matrix
500 mg

Other Ingredients

Vegan Capsule
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Dosage recommendations: Take 4 capsules daily with a meal. For best results, use OptygenHP during all intense training. OptygenHP should be used consistently for many months. If you start taking OptygenHP a week before a race, benefits will be minimal.

Formulation Notes

The new and improved OptygenHP has been engineered to optimize performance for endurance athletes.

This next-generation formula has been upgraded with Ashwagandha to modulate cortisol, improve power and enhance VO2 max. In addition, there's a clinically effective dose of premium grade Rhodiola & Cordyceps because clinical research shows the combination of these two endurance-specific adaptogens improves aerobic performance. Each serving of OptygenHP also delivers 1500mg of Beta-Alanine to boost strength and enhance exercise capacity.

Increases VO2 max Improves oxygen utilization & anaerobic threshold Modulates cortisol & reduces lactic acid

Additional Information

Optimize + Oxygen=OptygenHP

References: 1. Choudhary B, .et al. Effect of Ashwagandha in improving cardiorespiratory endurance in healthy athletic adults. Ayurvedic, 2015. 2. Shenoy S. et. al. Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists. Journal of Ayurvedic Integrated Medicine. 2012. 3. Chen et. al., Rhodiola and Cordyceps based supplement boosts aerobic exercise performance after short-term high altitude training. Journal of High Alt Medical Biology. 2014. 4. Ghiasvand R, Askari G, Malekzadeh J, Hajishafiee M, Daneshvar P, Akbari F, Bahreynian M. International Journal of Preventive Medicine. 2012 Aug;3(8):559-63. Effects of Six Weeks of b-alanine Administration on VO(2) max, Time to Exhaustion and Lactate Concentrations in Physical Education Students.

New & improved HP-High performance

Made in the USA

Store in a cool dry place.

Metadata

Product Details

UPC / SKU1 00000 82019 3
DSLD Entry Date2019-12-22
Product TypeOther Combinations
FormCapsule
BrandFirst Endurance
DSLD ID209152
Data Updated2026-04-11
Research

Research Evidence

212
Research Sources
54
Avg Quality
102
Meta Analysis
79
Systematic Review
19
Rct
3
Narrative Review
3
Regulatory Source
2
Other
2
Clinical Trial
1
Openfda Safety
A 1-year outcomes with the Absorb bioresorbable scaffold in patients with coronary artery disease: a patient-level, pooled meta-analysis
Meta Analysis Lancet (London, England) 2016 PubMed DOI
B Interventions for preventing weight gain after smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Prenatal metal(loid) exposure and preterm birth: a systematic review of the epidemiologic evidence
Systematic Review Journal of exposure science & environmental epidemiology 2025 PubMed DOI
B Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
B Chromium picolinate supplementation for overweight or obese adults
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
B Metalloestrogens exposure and risk of gestational diabetes mellitus: Evidence emerging from the systematic review and meta-analysis
Meta Analysis Environmental research 2024 PubMed DOI
B Trace elements in schizophrenia: a systematic review and meta-analysis of 39 studies (N = 5151 participants)
Meta Analysis Nutrition reviews 2020 PubMed DOI
B A meta-analysis of heavy metals pollution in farmland and urban soils in China over the past 20 years
Meta Analysis Journal of environmental sciences (China) 2021 PubMed DOI
B The spatiotemporal variation in heavy metals in China's farmland soil over the past 20 years: A meta-analysis
Meta Analysis The Science of the total environment 2022 PubMed DOI
B Human health risk assessment from potentially toxic elements in the soils of Sudan: A meta-analysis
Meta Analysis The Science of the total environment 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.