OptygenHP

product on market Capsule First Endurance 🟢 Safety: 100/100
Brand: First Endurance
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

4 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

200 mcg (167% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
150 mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 150mg
150 mg
📊 Market median: 300.0mg (122 products) 📚 22 studies (Tier A: 0, B: 7)
This product: 150mg
Cordyceps
800 mg
1500 mg
📊 Market median: 1500.0mg (104 products) 📚 21 studies (Tier A: 0, B: 2)
This product: 1500mg
ActiGin Proprietary Matrix
50 mg
ATPro Matrix
500 mg

Other Ingredients

Vegan Capsule

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (81% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Dosage recommendations: Take 4 capsules daily with a meal. For best results, use OptygenHP during all intense training. OptygenHP should be used consistently for many months. If you start taking OptygenHP a week before a race, benefits will be minimal.

🧪 Formulation Notes

The new and improved OptygenHP has been engineered to optimize performance for endurance athletes.

This next-generation formula has been upgraded with Ashwagandha to modulate cortisol, improve power and enhance VO2 max. In addition, there's a clinically effective dose of premium grade Rhodiola & Cordyceps because clinical research shows the combination of these two endurance-specific adaptogens improves aerobic performance. Each serving of OptygenHP also delivers 1500mg of Beta-Alanine to boost strength and enhance exercise capacity.

Increases VO2 max Improves oxygen utilization & anaerobic threshold Modulates cortisol & reduces lactic acid

Additional Information

Optimize + Oxygen=OptygenHP

References: 1. Choudhary B, .et al. Effect of Ashwagandha in improving cardiorespiratory endurance in healthy athletic adults. Ayurvedic, 2015. 2. Shenoy S. et. al. Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists. Journal of Ayurvedic Integrated Medicine. 2012. 3. Chen et. al., Rhodiola and Cordyceps based supplement boosts aerobic exercise performance after short-term high altitude training. Journal of High Alt Medical Biology. 2014. 4. Ghiasvand R, Askari G, Malekzadeh J, Hajishafiee M, Daneshvar P, Akbari F, Bahreynian M. International Journal of Preventive Medicine. 2012 Aug;3(8):559-63. Effects of Six Weeks of b-alanine Administration on VO(2) max, Time to Exhaustion and Lactate Concentrations in Physical Education Students.

New & improved HP-High performance

Made in the USA

Store in a cool dry place.

Product Details

UPC / SKU 1 00000 82019 3
DSLD Entry Date 2019-12-22
Product Type Other Combinations
Form Capsule
Brand First Endurance
DSLD ID 209152
Data Updated 2026-04-11

Research Evidence

212 Research Sources
54 Avg Quality Score
102 Meta Analysis
79 Systematic Review
19 Rct
3 Narrative Review
3 Regulatory Source
2 Other
2 Clinical Trial
1 Openfda Safety
A 1-year outcomes with the Absorb bioresorbable scaffold in patients with coronary artery disease: a patient-level, pooled meta-analysis
Meta Analysis Lancet (London, England) 2016
PubMed DOI
B Interventions for preventing weight gain after smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Prenatal metal(loid) exposure and preterm birth: a systematic review of the epidemiologic evidence
Systematic Review Journal of exposure science & environmental epidemiology 2025
PubMed DOI
B Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
B Chromium picolinate supplementation for overweight or obese adults
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI
B Metalloestrogens exposure and risk of gestational diabetes mellitus: Evidence emerging from the systematic review and meta-analysis
Meta Analysis Environmental research 2024
PubMed DOI
B Trace elements in schizophrenia: a systematic review and meta-analysis of 39 studies (N = 5151 participants)
Meta Analysis Nutrition reviews 2020
PubMed DOI
B A meta-analysis of heavy metals pollution in farmland and urban soils in China over the past 20 years
Meta Analysis Journal of environmental sciences (China) 2021
PubMed DOI
B The spatiotemporal variation in heavy metals in China's farmland soil over the past 20 years: A meta-analysis
Meta Analysis The Science of the total environment 2022
PubMed DOI
B Human health risk assessment from potentially toxic elements in the soils of Sudan: A meta-analysis
Meta Analysis The Science of the total environment 2025
PubMed DOI
View all evidence for Chromium →

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