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PearlBiotic Spheres

product on market Tablet or Pill Whitaker Nutrition Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

The probiotic blend and fructooligosaccharides are designed to support gut microbiota and digestive health. While research on these components is generally strong, the specific evidence coverage for this formulation is limited. The ingredient profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for PearlBiotic Spheres
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 80.0mg (20 products) 337 studies (A:8, B:183)
Market median: 100.0mg (1 products) 42 studies (A:1, B:15)

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Pectin Stearic Acid Sodium Carbonate Guar Gum Turmeric
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Doctor's suggested use: Take 1 time-released tablet daily with water prior to any meal. Do not chew or crush.

Warnings & Precautions

Precautions: Consult a health care practitioner if you are pregnant or nursing, have a serious medical condition, or use any medications.

Keep out of reach of children.

Contains: Milk Contains trace amounts of milk from the fermentation process.

Formulation Notes

Delivering 2 billion CFU of time-released, live probiotics in 7 strains - guaranteed

Contains: Milk Contains trace amounts of milk from the fermentation process.

GF Gluten free

Additional Information

Unconditionally guaranteed for purity and labeled potency.

Store with cap tightly closed in a cool, dry place. No refrigeration necessary.

Due to the nature of these ingredients, color variation may occur.

For digestive support

GF Gluten free

Almost out? Call 1-800-722-8008 or visit drwhitaker.com Choose refill & save, get free shipping forever

Metadata

Product Details

UPC / SKU6 78829 21271 5
DSLD Entry Date2019-10-23
Product TypeOther Combinations
FormTablet or Pill
DSLD ID208072
Data Updated2026-04-11
Research

Research Evidence

120
Research Sources
51
Avg Quality
47
Clinical Trial
38
Rct
20
Meta Analysis
13
Systematic Review
2
Cochrane Review
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Prebiotics for induction and maintenance of remission in ulcerative colitis
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
A Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Probiotics for management of functional abdominal pain disorders in children
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis
Meta Analysis The American journal of clinical nutrition 2018 PubMed DOI
B Effect of psyllium (Plantago ovata) fiber on LDL cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoprotein B: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis The American journal of clinical nutrition 2018 PubMed DOI
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Prebiotics, probiotics, fermented foods and cognitive outcomes: A meta-analysis of randomized controlled trials
Meta Analysis Neuroscience and biobehavioral reviews 2020 PubMed DOI
B Synbiotics, prebiotics and probiotics for people with chronic kidney disease
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Effects of Prebiotics and Probiotics on Symptoms of Depression and Anxiety in Clinically Diagnosed Samples: Systematic Review and Meta-analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.