Glucosamine Chondroitin with Vitamin C and Manganese by Mason Natural

100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
40% of ingredients have research evidence

A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin are commonly used to support joint health, though clinical evidence for their efficacy remains limited. Vitamin C and manganese serve as essential cofactors for connective tissue synthesis and antioxidant protection. These ingredients are generally well-tolerated, reflecting a high safety profile for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Open Full PDF View on NIH DSLD →

Details

Label Data

2 Capsule(s)

Serving Size

Servings

Other Combinations

Product Type

40%

Evidence Coverage

Ingredients

Supplement Facts — Evidence Check

Vitamin C

66 mg (110% DV)

Manganese

3 mg (150% DV)

1.3× RDA — within safe limits 9 studies — no high-quality reviews

Sodium

30 mg (1.3% DV)

Glucosamine Sulfate 2KCl

500 mg

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)

Chondroitin Sulfate

400 mg

Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Magnesium Stearate Syloid Stearic Acid Gelatin

Claims

Label Claims — Verification

Unverified Nutrient

Unverified All Other

Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 2 capsules 3 times daily, preferably with meals.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep Out of the Reach of Children

Formulation Notes

Glucosamine Chondroitin with Vitamin C and Manganese

Additional Information

Regular Strength

Soothes Joint Discomfort Original Formula

May Support Joint Health

Metadata

Product Details

DSLD Entry Date2019-11-21

Product TypeOther Combinations

FormCapsule

BrandMason Natural

DSLD ID207947

Data Updated2026-04-11

Research

Research Evidence

Research Sources

Avg Quality

Rct

Meta Analysis

Clinical Trial

Systematic Review

Regulatory Source

Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005 PubMed

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006 PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023 PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009 DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016 PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI

View all evidence for Glucosamine →

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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.