🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 29% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Label Data

3 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
29% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Calcium
170 mg (13% DV)
Sodium
85 mg (4% DV)
Potassium
260 mg (6% DV)
1.5 Gram(s)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1.5mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 1.2mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Flim Coat Magnesium Stearate Silica

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions for Use: As a dietary supplement, take 3 Signature Glucosamine & Chondroitin tablets daily.

⚠️ Warnings & Precautions

Warnings: Consult your physician before using this product if you're taking any medications or are under a physician's care for a medical condition. Not for use by those under the age of 18 or by women that are pregnant, trying to get pregnant or nursing.

Not for use by those under the age of 18 or by women that are pregnant, trying to get pregnant or nursing.

Persons with a known allergy to shellfish should not use this product.

Contains Crustacean shellfish (crab and shrimp).

🧪 Formulation Notes

Every product is transparent, filler-free, and formulated with effective doses of research-backed ingredients you can trust.

Contains Crustacean shellfish (crab and shrimp).

Additional Information

A signature is a promise. A symbol of your identity. Your mark on the world. Bodybuilding.com was founded on a single promise: Trust. It's who we are and it's in our blood. Our Signature line is built on the same promise. Every product is transparent, filler-free, and formulated with effective doses of research-backed ingredients you can trust. We create the highest quality supplements, so you can focus on leaving a mark of your own.

Manufactured in the USA in a GMP registered facility with domestic and international ingredients.

Protects joint health Promotes cartilage heatlh

Product Details

UPC / SKU 8 53002 00749 8
DSLD Entry Date 2019-10-23
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 207631
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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