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Glucosamine Chondroitin Complex plus MSM Advanced Triple Strength

product on market Tablet or Pill 21st Century Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 22% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains Vitamin C and manganese, which provide moderate evidence for supporting connective tissue and bone health. However, the overall evidence coverage for this specific ingredient profile is very limited. The supplement maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Glucosamine Chondroitin Complex plus MSM Advanced Triple Strength
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
40
Servings
Other Combinations
Product Type
22%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
Vitamin C
60 mg (70% DV)
2 mg (90% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Sodium
50 mg (2% DV)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Proprietary Blend
1250 mg
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Cellulose Polyplasdone Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, adults take two (2) tablets daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

2 per day

Warnings & Precautions

Do not exceed recommended dosage.

Warning: If you are diabetic, consult your physician before using this product.

If you have a Shellfish allergy please consult your physician before using this product.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Contains shellfish (shrimp, crab, lobster, crayfish).

Formulation Notes

Glucosamine Chondroitin Complex Plus MSM Advanced Triple Strength combines Glucosamine Hydrochloride with complimentary nutrients that help support joints and cartilage.

No added Artificial Flavors or Preservatives.

Contains shellfish (shrimp, crab, lobster, crayfish).

Additional Information

Individual results may vary.

Store at room temperature.

Guaranteed quality Laboratory tested

Compare vs. Osteo Bi-Flex Advanced 3X

Metadata

Product Details

UPC / SKU7 40985 27290 9
DSLD Entry Date2019-10-23
Product TypeOther Combinations
FormTablet or Pill
Brand21st Century
DSLD ID206833
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.