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Standardized Black Cohosh & Soy Isoflavones 100% Vegetarian

product on market Capsule 21st Century Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Black cohosh and soy isoflavones are researched for the management of menopausal symptoms, specifically hot flashes. Evidence for these ingredients is generally considered limited to moderate in strength. These components act as phytoestrogens to support hormonal balance.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Standardized Black Cohosh & Soy Isoflavones 100% Vegetarian
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
100
Servings
Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 80.0mg (136 products)
Market median: 60.0mg (94 products) 13 studies (A:0, B:7)

Other Ingredients

Rice Bran Oat Fiber Vegetable Cellulose Magnesium Silicate Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two (2) vegetarian capsules daily - one (1) in the morning and one (1) in the evening with meals for maximum daily results, or as directed by a medical practitioner. Do not exceed recommended dosage

Warnings & Precautions

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

This product contains a soy ingredient.

Formulation Notes

100% VEGETARIAN

No added Sugar, Salt, Yeast, Preservatives, Artificial Flavors or Colors.

Black Cohosh Extract (Cimicifuga racemosa) is a beneficial supplement during menopause.*

Maximum Strength Formula with Isoflavones for Nutritional Support During Menopause*

Additional Information

0312

Black Cohosh is recommended by the German Kommission E and is backed by 40 years of research. Allow between 4 and 6 weeks for dramatic results. 21st Century's standardized herbal extracts are thoroughly tested to assure specific levels of the important active ingredients are present for maximum benefit.

Store at room temperature.

HERBAL EXTRACT

200 COUNT

MADE IN USA

LABORATORY TESTED GUARANTEED QUALITY

Metadata

Product Details

UPC / SKU7 40985 21724 5
DSLD Entry Date2013-04-25
Product TypeBotanical
FormCapsule
DSLD ID20664
Data Updated2026-04-11
Research

Research Evidence

16
Research Sources
51
Avg Quality
7
Meta Analysis
6
Rct
2
Clinical Trial
1
Systematic Review
B Soy isoflavones prevent bone resorption and loss, a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2020 PubMed DOI
B Isoflavone intervention and its impact on bone mineral density in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2024 PubMed DOI
B Effects of Soy Isoflavones on Biochemical Markers of Bone Metabolism in Postmenopausal Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis International journal of environmental research and public health 2021 PubMed DOI
B Effects of isoflavone interventions on bone turnover markers and factors regulating bone metabolism in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Archives of osteoporosis 2024 PubMed DOI
B Effects of isoflavone interventions on bone mineral density in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2020 PubMed DOI
C Effects of soy isoflavone supplements on bone turnover markers in menopausal women: systematic review and meta-analysis of randomized controlled trials
Meta Analysis Bone 2010 PubMed DOI
C Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men
Rct The American journal of clinical nutrition 1998 PubMed DOI
C Impact of phytoestrogens on treatment of urogenital menopause symptoms: A systematic review of randomized clinical trials
Systematic Review European journal of obstetrics, gynecology, and reproductive biology 2021 PubMed DOI
C Identification of the Key Active Pharmaceutical Ingredients of Yishen Qutong Granule, A Chinese Medicine Formula, In The Treatment of Primary Lung Cancer
Meta Analysis Combinatorial chemistry & high throughput screening 2023 PubMed DOI
C Assessing the combined effects of Black Cohosh, Soy Isoflavones, and SDG Lignans on menopausal symptoms: a randomized, double-blind, placebo-controlled clinical trial.
Rct European journal of nutrition PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.