Home/ Supplements/ Folate/ Folic Acid 800 mcg

Folic Acid 800 mcg

product on market Tablet or Pill 21st Century Safety: 80/100
80/100

This product is generally safe

  • Folate: 1334mg is 1334.0× the Tolerable Upper Intake Level (1.0mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Folate is supported by strong evidence for preventing neural tube defects during pregnancy, while calcium supports bone health and mineral balance. However, the overall evidence coverage for this specific formulation is limited. The ingredients are generally considered safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 1334mg is 1334.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Folic Acid 800 mcg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1334 mcg DFE (333% DV)
Exceeds UL by 1334.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
Calcium
100 mg (8% DV)

Other Ingredients

Cellulose Maltodextrin Croscarmellose Sodium Stearic Acid Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a vitamin supplement, adults take one (1) tablet daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Folic Acid should not exceed 1,000 mcg per day.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Formulation Notes

No added Sugar, Yeast, Preservatives, Artificial Flavors or Colors.

Gluten free

Folic Acid is an essential B vitamin that supports heart health.

Additional Information

Individual results may vary.

Store at room temperature.

Heart Health Support

Gluten free

Guaranteed quality Laboratory tested

Metadata

Product Details

UPC / SKU7 40985 22563 9
DSLD Entry Date2019-08-23
Product TypeSingle Vitamin and Mineral
FormTablet or Pill
Brand21st Century
DSLD ID205960
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
View all evidence for Folate →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.