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GS-500 & Chondroitin

product on market Tablet or Pill Nature's Way Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine sulfate is researched for its potential to support joint health and cartilage maintenance, though evidence for its efficacy remains mixed. Other listed components, such as sodium and chloride, are common dietary minerals. Overall, the clinical evidence supporting this specific ingredient profile for joint support is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for GS-500 & Chondroitin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
20
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
4 Gram(s) (1% DV)
277 mg (12% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Sodium
290 mg (13% DV)
1.5 Gram(s)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
1.2 Gram(s)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Cellulose Sodium Croscarmellose Hypromellose Titanium Dioxide Glycerin Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 3 tablets daily. May be taken as 1 tablet three times daily.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Contains shellfish (shrimp and crab).

Formulation Notes

500 mg stabilized glucosamine sulfate per tablet 400 mg chondroitin sulfate per tablet

Gluten free. No sugar, yeast, wheat, corn, dairy products, or artificial flavors, or preservatives.

Stabilized Glucosamine

Contains shellfish (shrimp and crab).

Additional Information

Helps support healthy joints and cartilage

Since 1969

Helps Support Healthy Joints & Cartilage

Metadata

Product Details

UPC / SKU7 63948 01726 3
DSLD Entry Date2019-08-23
Product TypeOther Combinations
FormTablet or Pill
BrandNature's Way
DSLD ID205146
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
48
Avg Quality
21
Rct
10
Meta Analysis
2
Clinical Trial
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
C Update on the role of pharmaceutical-grade chondroitin sulfate in the symptomatic management of knee osteoarthritis
Meta Analysis Aging clinical and experimental research 2019 PubMed DOI
C Evaluation of efficacy and safety of glucosamine sulfate, chondroitin sulfate, and their combination regimen in the management of knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Inflammopharmacology 2024 PubMed DOI
C Does incorporating collagen and chondroitin sulfate matrix in implant surfaces enhance osseointegration? A systematic review and meta-analysis
Meta Analysis International journal of oral and maxillofacial surgery 2018 PubMed DOI
C Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials
Meta Analysis Rheumatology international 2018 PubMed DOI
View all evidence for Chondroitin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.