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Vitamin B-12 250 mcg

product on market Tablet or Pill Major Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin B12 supports nerve function and red blood cell formation, while calcium and phosphorus contribute to bone health. There is strong research evidence for these nutrients, though the overall evidence coverage for this specific profile is limited. The formulation maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Vitamin B-12 250 mcg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
40 mg (3% DV)
30 mg (2% DV)
Market median: 99.0mg (503 products) 13 studies (A:0, B:3)

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) tablet daily, preferably with a meal.

Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

AS with any supplement, if you are pregnant, nursing, taking medication or have a medical condition, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Tamper resistant: Do not use if clear neck seal is broken or missing.

Formulation Notes

Free of: Yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial color, artificial flavor, sodium (less than 5 mg per serving).

Vitamin B-12 contributes to the health of the nervous system. Vitamin B-12 is essential for normal formation of blood cells.

Additional Information

Re-Order No. 700078 Potency guaranteed Contributes to the health of the nervous system

Store at room temperature in a dry place.

Prod. No. 700078 M-95 Rev. 05/17

Metadata

Product Details

UPC / SKU3 09044 21813 7
DSLD Entry Date2019-04-25
Product TypeOther Combinations
FormTablet or Pill
BrandMajor
DSLD ID201745
Data Updated2026-04-11
Research

Research Evidence

237
Research Sources
53
Avg Quality
83
Meta Analysis
74
Systematic Review
45
Rct
29
Clinical Trial
2
Guideline
2
Regulatory Source
1
Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021 PubMed DOI
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024 PubMed DOI
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020 PubMed DOI
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024 PubMed DOI
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023 PubMed DOI
View all evidence for Vitamin B12 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.