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St. John's Wort

product on market Liquid Botanic Choice Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for St. John's Wort
Open Full PDF View on NIH DSLD →
Details

Label Data

1 mL
Serving Size
Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Market median: 300.0mg (240 products) 20 studies — no high-quality reviews

Other Ingredients

Glycerin Water
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take 1 mL (approx. 28 drops) three times daily, in a small amount of water.

Shake well.

Warnings & Precautions

Warning: Avoid excessive exposure to UV light (i.e., sunlight, tanning) when using this product. May cause skin to become photosensitive.

If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

Discontinue use 2 weeks prior to any surgery.

Use only if seal is unbroken.

Keep out of reach of children

Formulation Notes

Alcohol free liquid extract

Additional Information

Trusted since 1910 4:1 extract

Best if used by date on bottle. Store in a dry, cool place.

C-104661

Metadata

Product Details

UPC / SKU7 03308 20073 7
DSLD Entry Date2019-04-25
Product TypeBotanical
FormLiquid
BrandBotanic Choice
DSLD ID199560
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
View all evidence for St Johns Wort →
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St Johns Wort research Best St Johns Wort All St Johns Wort products More from Botanic Choice View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.