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Multi-Enzyme

product on market Tablet or Pill The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 8% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines digestive enzymes like pancreatin and amylase with betaine HCl to support the breakdown of proteins, fats, and carbohydrates. Research provides moderate evidence that these components assist individuals with pancreatic insufficiency or low stomach acid. Calcium and phosphorus serve as supplemental minerals to support general metabolic functions.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Multi-Enzyme
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
150
Servings
Other Combinations
Product Type
8%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
200 mg (15% DV)
156 mg (12% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:3)
Pancreatin
100 mg
400 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Amylase
Protease
Pepsin
100 mg
Papain
Ox Bile powder
30 mg
Lipase
Cellulase

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silicon Dioxide Aqueous Coating natural Peppermint flavor
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two (2) tablets after each meal. Do not take on an empty stomach.

Warnings & Precautions

Contains: Milk.

Do not take on an empty stomach.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

Gluten free Soy free Nut free

Contains: Milk.

Does not contain: Gluten, Artificial Colors or Flavors.

Additional Information

Specialty

Protein Carbohydrate Fat digestion

Store in a cool, dry place.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Item No. VS-1195 1040236 FS 37

Metadata

Product Details

UPC / SKU7 66536 01195 7
DSLD Entry Date2019-02-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID184253
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.