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AHCC Plus 500 mg

product on market Capsule Source Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula features AHCC, a mushroom derivative with limited research suggesting potential immune system support. Vitamin E and selenium provide antioxidant properties with moderate evidence for cellular protection. Overall, the evidence coverage for this specific ingredient combination is very low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for AHCC Plus 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
15
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
160 IU (530% DV)
7.1× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
80 mcg (114% DV)
1.5× RDA — within safe limits 173 studies (A:0, B:67)
AHCC Proprietary Blend
1 Gram(s)
10.7× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
Within RDA (0.3× RDA) 179 studies (A:3, B:90)

Other Ingredients

Gelatin Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 2 capsules twice daily on an empty stomach.

Warnings & Precautions

Contains soy.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Formulation Notes

Contains soy.

AHCC (Active Hexose Correlated Compound) is a proprietary compound produced by cultivation of shitake mushroom mycelia, grown in rice bran extract. Considered a superfood supplement in Japan, AHCC has been researched extensively for its immune enhancement properties. Preliminary research indicates that AHCC may significantly increase Natural Killer (NK) Cell activity. There is also evidence to suggest that AHCC may increase macrophage activity, enhance cytokine production, and support the healthy functioning of the liver as well as act as an antioxidant.

Additional Information

Increases natural killer cell activity

SN1786 REV C172

Metadata

Product Details

UPC / SKU0 21078 01786 8
DSLD Entry Date2019-01-07
Product TypeOther Combinations
FormCapsule
BrandSource Naturals
DSLD ID181700
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
View all evidence for Vitamin E →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.