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Digestive Probiotics + Energy B12 Dual Action

product on market Gummy or Jelly Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin B12 supports energy metabolism, while Bacillus coagulans IS-2 is used to promote digestive health. There is strong evidence for B12's role in cellular function, though overall evidence coverage for this specific formulation is limited. The profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Digestive Probiotics + Energy B12 Dual Action
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Gummie(s)
Serving Size
25
Servings
Other Combinations
Product Type
20%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
20 Calorie(s)
Total Carbohydrates
5 Gram(s) (2% DV)
Sodium
15 mg (1% DV)
1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
Bacillus coagulans IS-2

Other Ingredients

Glucose Syrup Sugar Pineapple juice concentrate Wheat Starch Gelatin Invert Sugar Propylene Glycol Citric Acid Sodium Citrate Colors added Natural flavors Coconut Oil White Beeswax Carnauba Wax
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Chew two gummies daily.

Warnings & Precautions

Store in a cool, dry place, at or below 75(0)F (23(0)C), out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Contains: Wheat.

Formulation Notes

Energy B12 Vitamin B12 supports: Cellular energy production

Contains: Wheat.

Additional Information

List No. 4288 L200 Cat. A858 5B088

New Natural fruit flavors 4 billion CFU per serving Adult gummies Probiotic Naturally helps support: Digestive health +

Raspberry & Cherry with other natural flavors

Keep bottle tightly closed. Store in a cool, dry place, at or below 75(0)F (23(0)C), out of reach of children.

Made in Australia. Package and quality tested in the U.S.A. Digestive Probiotic Gummies with Vitamin B12 are made to Nature Made's guaranteed purity and potency standards.

Formulated to provide at least 4 billion live cells per serving if continuously stored in a cool, dry place at or below 75(0)F (23(0)C) and consumed prior to expiration date. Storage and handling conditions can vary, and may affect the total amount of cells delivered at time of consumption.

Metadata

Product Details

UPC / SKU0 31604 04288 2
DSLD Entry Date2018-09-21
Product TypeOther Combinations
FormGummy or Jelly
BrandNature Made
DSLD ID180385
Data Updated2026-04-11
Research

Research Evidence

691
Research Sources
52
Avg Quality
255
Clinical Trial
205
Meta Analysis
123
Rct
81
Systematic Review
18
Cochrane Review
2
Guideline
2
Regulatory Source
1
Other
1
Narrative Review
1
Openfda Safety
A Probiotics for preventing acute upper respiratory tract infections
Systematic Review The Cochrane database of systematic reviews 2022 PubMed DOI
A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Probiotics for maintenance of remission in ulcerative colitis
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Probiotics for induction of remission in ulcerative colitis
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Probiotics for treating eczema
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Probiotics for treating acute infectious diarrhoea
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Probiotics to prevent infantile colic
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
View all evidence for Probiotics →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.