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Calm & Clever

product on market Other (e.g. tea bag) Akeso Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 29% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains B-vitamins and Vitamin C, which support general metabolic function. Bacopa monnieri and Huperzine A are included for cognitive support, though research evidence for these botanicals is generally moderate to limited. The ingredient profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calm & Clever
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
30
Servings
Other Combinations
Product Type
29%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
250 mg (250% DV)
25 mg (1250% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg (250% DV)
5.0× RDA — above typical dose 2 studies — no high-quality reviews
Bacopa monnieri
320 mg
200 mcg
Market median: 0.15mg (41 products)
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)
Vinpocetine
15 mg

Other Ingredients

Calcium Phosphate powdered Cellulose Stearic Acid Silicon Dioxide Croscarmellose Sodium Magnesium Stearate Hydroxypropyl Methylcellulose Titanium Dioxide Caramel Riboflavin Carmine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Usage: Take 2 caplets a day with food. Though some users can experience noticeable benefits in as few as 1-2 days, please allow 2-3 weeks to achieve optimal benefits.

Warnings & Precautions

Warnings: As with any dietary supplement, please consult your physician before use.

This product is not for use by children under the age of 10, or pregnant or lactating women.

This product is not for use by children under the age of 10, or pregnant or lactating women.

Formulation Notes

Does Not Contain: Yeast, milk, corn, wheat, gluten, soy, salt, artificial flavorings or preservatives.

100% drug-free

With Vinpocetine

Additional Information

Calm & Clever is an effective dietary supplement using clinical doses of ingredients shown in human studies to relieve stress, occasional anxiety and support memory recall of words, names and facts, which can be negatively affected by stress and aging.

Where nature & medicine unite

Relieves stress and occasional anxiety Enhances recall of words/names/facts Clinical strength

Metadata

Product Details

UPC / SKU8 55586 00012 4
DSLD Entry Date2018-04-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandAkeso
DSLD ID175366
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.