Betaine HCl with Pepsin
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- Limited research evidence available for ingredients
B
Label Compliance Grade
Product Label
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Label Data
1 Tablet(s)
Serving Size
100
Servings
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Supplement Facts — Evidence Check
600 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Pepsin
60 mg
Other Ingredients
Stearic Acid
Croscarmellose Sodium
Magnesium Stearate
Silicon Dioxide
Bromelain
Papain
Pharmaceutical Glaze
Label Claims — Verification
❓
All Other
All Other (100% of products)
Structure/Function (82% of products)
Nutrient (8% of products)
Target Groups
Adult (18 - 50 Years)
Sugar Free
Product Information
📋 Directions for Use
Directions As a dietary supplement, take one (1) or two (2) tablets daily, preferably with a meal.
⚠️ Warnings & Precautions
Warning DO not use if you are pregnant nursing or if you have gastritis or peptic ulcer.
Keep out of reach of children.
🧪 Formulation Notes
Does Not Contain: Yeast, corn, wheat, sugar, salt, starch, citrus, fish, preservatives, artificial colors or flavors added.
Additional Information
Item #: VS-1196 / 1040277
Known as Trimethylglycine (TMG) Enzymes
Contains betaine hydrochloride from sugar beets, along with pepsin for digestive support. Formulated for quick delivery and absorption.
SINCE 1977
Product Details
DSLD Entry Date
2012-10-25
Product Type
Non-Nutrient/Non-Botanical
Form
Tablet or Pill
Brand
The Vitamin Shoppe
DSLD ID
13047
Data Updated
2026-04-11
Research Evidence
23
Research Sources
47
Avg Quality Score
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B
Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
C
Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
C
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
C
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
C
Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
C
Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
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