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C 500 mg & E 400 IU

product on market Softgel Capsule Spring Valley Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C and E are well-studied antioxidants that support immune function and protect cells from oxidative stress. Rose hips provide additional vitamin C and flavonoids, though evidence for their specific therapeutic effects is more limited. These ingredients are generally recognized as safe for most adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for C 500 mg & E 400 IU
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Botanical with Nutrients
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (833% DV)
400 IU (1333% DV)
17.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
Rose Hips
20 mg

Other Ingredients

Gelatin Glycerin Soybean Oil Contains <2% of:
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

SUGGESTED USE: For adults, take one (1) softgel one to two times daily, preferably with a meal. As a reminder, discuss the supplements and medications you take with your health care providers.

Warnings & Precautions

Discontinue use and consult your doctor if any adverse reactions occur.

KEEP OUT OF THE REACH OF CHILDREN.

WARNING: If you are pregnant, nursing, taking any medications, planning any medical procedure or have any medical condition, consult your doctor before use.

FOR YOUR PROTECTION, DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

Formulation Notes

No Gluten, No Yeast, No Wheat, No Milk or Milk Derivatives, No Lactose, No Sugar, No Preservatives Added, No Artificial Flavor, No Sodium (less than 5 mg per serving)

Additional Information

HEART HEALTH* Vitamin C plays an important role in supporting immune function.* As an antioxidant, Vitamin C helps neutralize harmful free radicals in cell.* Vitamin E is a fat-soluble antioxidant that fights cell-damaging free radicals in the body.* Vitamin E helps stabilize cell membranes and regulates oxidation reactions in the body.*

VITAMIN #1 BRAND

STORE AT ROOM TEMPERATURE, TIGHTLY CLOSED AND AVOID EXCESSIVE HEAT.

QUALITY ASSURANCE GUARANTEE

Produced under strict quality guidelines. Verified by an independent ISO 9001:2000 certified laboratory.

UNCONDITIONALLY GUARANTEED BY REFUND OR REPLACEMENT

Item No. 1260 B1274W 08C

Metadata

Product Details

UPC / SKU6 05388 76692 2
DSLD Entry Date2012-08-24
Product TypeBotanical with Nutrients
FormSoftgel Capsule
DSLD ID12178
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.