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Pregnenolone 10 mg

product on market Capsule LifeLink Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for Pregnenolone 10 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg
Market median: 30.0mg (45 products)

Other Ingredients

Microcrystalline Cellulose Gelatin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Use: 1 to 2 capsules in the afternoon or as directed by a health care professional.

Warnings & Precautions

Do NOT take if at risk for hormonally related cancers such as reproductive or prostate abnormalities, if under the age of 40, or if pregnant, lactating or trying to conceive.

Formulation Notes

Pregnenolone 10 mg

Additional Information

Pregnenolone is metabolized in two directions: production of DHEA and its metabolites, and production of progesterone and its metabolites.

Metadata

Product Details

UPC / SKU6 39793 20302 4
DSLD Entry Date2012-08-24
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID11745
Data Updated2026-04-11
Research

Research Evidence

9
Research Sources
38
Avg Quality
5
Rct
2
Narrative Review
2
Other
B Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial
Rct JAMA network open 2020 PubMed DOI
C Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder
Rct Biomolecules 2022 PubMed DOI
C Pregnenolone for cognition and mood in dual diagnosis patients
Rct Psychiatry research 2010 PubMed DOI
C Reduced urine pregnenolone concentration after clinical response in patients with depression: An open-label short-term prospective study
Rct Psychoneuroendocrinology 2023 PubMed DOI
C Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia
Rct Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009 PubMed DOI
D Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells
Other The Journal of biological chemistry 2023 PubMed DOI
D Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics
Other Alcohol (Fayetteville, N.Y.) 2016 PubMed DOI
D Pregnenolone sulfate in the brain: a controversial neurosteroid
Narrative Review Neurochemistry international 2008 PubMed
D Individual differences in cognitive aging: implication of pregnenolone sulfate
Narrative Review Progress in neurobiology 2003 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.