Supplements for Knee Osteoarthritis

What the Research Shows

Hyaluronic acid provides the strongest evidence for managing knee osteoarthritis pain and improving clinical indices, particularly through intra-articular injections or oral combinations with glucosamine and chondroitin. Glucosamine also shows moderate evidence for potential efficacy in pain and function, especially when paired with chondroitin, though some large-scale studies have found it to be non-inferior to a placebo. Additionally, burdock root tea has moderate evidence suggesting it may help reduce inflammation and oxidative stress. Other options have much less certain support. Celery seed extract, when used alongside Boswellia serrata, has weak evidence for assisting with cartilage degeneration and managing the condition. Pomegranate juice currently has insufficient evidence, as research is limited to small-scale studies that may affect certain clinical signs and joint enzymes.

AI-generated overview based on research evidence. Not medical advice.