OptygenHP

product on market Capsule First Endurance 🟢 Safety: 100/100
Brand: First Endurance
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

4 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

200 mcg (167% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
300 mg
📊 Market median: 300.0mg (122 products) 📚 22 studies (Tier A: 0, B: 7)
This product: 300mg
Cordyceps
800 mg
1500 mg
📊 Market median: 1500.0mg (104 products) 📚 21 studies (Tier A: 0, B: 2)
This product: 1500mg
ActiGin Proprietary Matrix
50 mg
ATPro Matrix
500 mg

Other Ingredients

Vegan Capsule

Label Claims — Verification

❓ Structure/Function
All Other (98% of products) Structure/Function (81% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Dosage Recommendations: Take 4 capsules daily with a meal. For best results, use OptygenHP during all intense training. OptygenHP should be used consistently for many months. If you start taking OptygenHP a week before a race, benefits will be minimal.

🧪 Formulation Notes

This next-generation OptygenHP has been upgraded with the most potent blend of Cordyceps mushroom available to maximize your VO2max and time to exhaustion. (1) In addition, there's a clinically effective dose of premium grade Rhodiola because the latest clinical research shows the combination of these two endurance-specific adaptogens improves aerobic performance. (2) Each serving also delivers 1500mg of Beta-Alanine to boost strength and enhance exercise capacity so you can exercise longer.

Additional Information

Optimize + Oxygen = OptygenHP The new and improved OptygenHP have been engineered to optimize performance for endurance athletes and is the best Optygen formula we've ever developed.

References: 1. Hirsch et. al., Cordyceps militaris improves tolerance to high-intensity exercise after acute and chronic supplementation, Journal of Dietary Supplements. 2016 2. Chen et. al., Rhodiola and Cordyceps based supplement boosts aerobic exercise performance after short-term high altitude training. Journal of High Alt Medical Biology. 2014.

36682017.2

New & Improved HP - High performance Increases VO2 max Improves oxygen utilization & anaerobic threshold Modulates cortisol & reduces lactic acid

Made in the USA

Store in a cool, dry place.

Product Details

UPC / SKU 1 00000 82017 9
DSLD Entry Date 2017-12-22
Product Type Other Combinations
Form Capsule
Brand First Endurance
DSLD ID 81282
Data Updated 2026-04-11

Research Evidence

212 Research Sources
54 Avg Quality Score
102 Meta Analysis
79 Systematic Review
19 Rct
3 Narrative Review
3 Regulatory Source
2 Other
2 Clinical Trial
1 Openfda Safety
A 1-year outcomes with the Absorb bioresorbable scaffold in patients with coronary artery disease: a patient-level, pooled meta-analysis
Meta Analysis Lancet (London, England) 2016
PubMed DOI
B Interventions for preventing weight gain after smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Prenatal metal(loid) exposure and preterm birth: a systematic review of the epidemiologic evidence
Systematic Review Journal of exposure science & environmental epidemiology 2025
PubMed DOI
B Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
B Chromium picolinate supplementation for overweight or obese adults
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI
B Metalloestrogens exposure and risk of gestational diabetes mellitus: Evidence emerging from the systematic review and meta-analysis
Meta Analysis Environmental research 2024
PubMed DOI
B Trace elements in schizophrenia: a systematic review and meta-analysis of 39 studies (N = 5151 participants)
Meta Analysis Nutrition reviews 2020
PubMed DOI
B A meta-analysis of heavy metals pollution in farmland and urban soils in China over the past 20 years
Meta Analysis Journal of environmental sciences (China) 2021
PubMed DOI
B The spatiotemporal variation in heavy metals in China's farmland soil over the past 20 years: A meta-analysis
Meta Analysis The Science of the total environment 2022
PubMed DOI
B Human health risk assessment from potentially toxic elements in the soils of Sudan: A meta-analysis
Meta Analysis The Science of the total environment 2025
PubMed DOI
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