Home/ Supplements/ Quercetin/ C Extra 500 mg Plus 500 mg Bioflavonoids

C Extra 500 mg Plus 500 mg Bioflavonoids

product on market Tablet or Pill Natural Factors Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C and citrus bioflavonoids are supported by moderate evidence for supporting immune function and antioxidant activity. Rutin, hesperidin, and rosehips provide additional flavonoid content, though clinical evidence for their individual efficacy in this combination is limited. The ingredient profile maintains a high safety rating.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for C Extra 500 mg Plus 500 mg Bioflavonoids
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
40%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (830% DV)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
50 mg
Market median: 500.0mg (19 products)
Rosehips
50 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)

Other Ingredients

Di-Calcium Phosphate Lactose Croscarmellose Sodium Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: 1 tablet daily or as directed by a health professional.

Warnings & Precautions

Sealed for your protection. Do not use if seal on cap is broken.

Formulation Notes

Natural Factors C Extra tablets contain 500mg of Vitamin C in a blend of Citrus Bioflavonoids, Rutin, Rosehips and Hesperidin to support the body's use of Vitamin C.

Contains no artificial preservatives or color, no dairy, sweeteners, wheat or yeast.

Additional Information

For freshness store in a cool, dry place.

Bioflavonoids and Vitamin C work synergistically to enhance each other's activity. Bioflavonoids are essential for proper absorption of Vitamin C and have been shown to keep collagen healthy, have antioxidant properties and to increase capillary strength.* Vitamin C is a potent, nutritional antioxidant supporting healthy bones, cartilage, teeth and gums. It helps protect cells against environmental pollutants and deficiencies in the daily diet.* All Natural Factors products are manufactured according to Canadian Health Protection Branch Good Manufacturing Practices (GMP), among the highest standards in the world.

(recycle) Recyclable container and label.

Purity & Potency Guaranteed

POTENT ANTIOXIDANT PROTECTION*

PRODUCT OF CANADA

R2

Metadata

Product Details

UPC / SKU0 68958 01311 4
DSLD Entry Date2012-04-26
Product TypeOther Combinations
FormTablet or Pill
DSLD ID8014
Data Updated2026-04-11
Research

Research Evidence

184
Research Sources
55
Avg Quality
91
Systematic Review
75
Meta Analysis
7
Rct
7
Clinical Trial
2
Cochrane Review
1
Openfda Safety
B Treatment of gouty arthritis with traditional Chinese medicine decoction: Meta-analysis, network pharmacology analysis, and molecular docking
Meta Analysis Medicine 2024 PubMed DOI
B Effects of quercetin supplementation on lipid profile: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2017 PubMed
B Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis
Meta Analysis BMC endocrine disorders 2024 PubMed DOI
B Quercetin and endurance exercise capacity: a systematic review and meta-analysis
Meta Analysis Medicine and science in sports and exercise 2011 PubMed DOI
B Dietary flavonoid intake and smoking-related cancer risk: a meta-analysis
Meta Analysis PloS one 2013 PubMed DOI
B Clinical efficacy evaluation and potential mechanism prediction on Guizhi-Shaoyao-Zhimu decoction in the treatment of gouty arthritis based on meta-analysis, network pharmacology analysis, and molecular docking
Meta Analysis Medicine 2023 PubMed DOI
B A Systematic Review: Quercetin-Secondary Metabolite of the Flavonol Class, with Multiple Health Benefits and Low Bioavailability
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Dietary flavonoid for preventing colorectal neoplasms.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Flavonoids for treating venous leg ulcers.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B The effects of quercetin supplementation on lipid profiles and inflammatory markers among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2020 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.