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ChronoSet

product on market Capsule Allergy Research Group Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Melatonin is supported by strong evidence for its ability to regulate sleep-wake cycles and reduce sleep onset latency. Research indicates it is generally effective for short-term management of circadian rhythm disruptions. The ingredient profile maintains a high safety score with minimal reported adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for ChronoSet
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
50
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2.6 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose L-Leucine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use As a dietary supplement, 1 or 2 capsules one hour before bedtime, or as directed by a healthcare practitioner.

Warnings & Precautions

Warning: Melatonin may have a strong sedating effect within 20 minutes of consumption. Not to be used during daytime.

Not recommended for women who are pregnant, wishing to become pregnant, or breastfeeding; for children or adolescents; or for those with a prior history of seizures.

Do not use while operating a motor vehicle or other machinery. In rare cases it may stimulate seasonal affective disorder, depression, or have stimulatory effects.

Formulation Notes

Melatonin formula

Hypoallergenic

Additional Information

Melatonin’s main function in the body is to support sleep.

Keep in a cool, dry place, tightly capped.

Rev. 005

Metadata

Product Details

UPC / SKU7 13947 71660 5
DSLD Entry Date2017-09-21
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID78817
Data Updated2026-04-11
Research

Research Evidence

291
Research Sources
55
Avg Quality
129
Meta Analysis
93
Systematic Review
51
Rct
11
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022 PubMed DOI
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022 PubMed DOI
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022 PubMed DOI
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023 PubMed DOI
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.