🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

0.25 mL Serving Size
60 Servings
Single Vitamin and Mineral Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

100 mg (18% DV)
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 100mg UL 3500mg
5 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 5mg

Other Ingredients

Glycerol purified Water

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For Skin, Hair, Nails and Joints: Take 5 drops, 2 times per day. Mix in with a 1/4 cup of liquid (preferably juice) and drink immediately with or without food. For Bones: Take 6 drops, 1 time per day. Mix in with a 1/4 cup of liquid (preferably juice) and drink immediately with or without food.

⚠️ Warnings & Precautions

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Keep out of the reach of children.

🧪 Formulation Notes

This product does not contain gluten, wheat, soy, corn, yeast, dairy, sugar, starch, egg, fish, shellfish, peanuts or tree nuts, animal products, GMOs or artificial colors, preservatives or sweeteners.

V Vegan Vegetarian

ch-OSA Advanced collagen generator

ch-OSA Original Formula

Additional Information

Store at 59-86(0)F (15-30(0)C). Protect from light and moisture.

V Vegan Vegetarian

isura Non-GMO - Mass spec Documentation - Lab tested

Reduces fine lines and wrinkles Thickens and strengthens hair Strengthens nails Promotes strong and flexible bones Promotes healthy joints Clinically proven

Made in Belgium

9185U-R2

Clinically proven results Strengthens hair First 36 weeks Break load (N) .58 .60 .65 .70 .73 Placebo 0.61 ch-OSA (2 caps/day) 0.69 13.1% stronger hair with ch-OSA

Reduces depth of wrinkles First 20 weeks Change in wrinkle depth -20% -15% -10% -5% 0 +5% +10% +15% +20% Placebo -11% ch-OSA (2 caps/day) 30% net improvement in wrinkle depth with ch-OSA

Improves bone mineral density at hip First 12 months Change is bone mineral density -1.5- -1.00 -.50 0 +.50 +1.00 Calcium & vitamin D -1.22% ch-OSA + calcium & vitamin D .78% 2.00% improvement in BMd at hip with ch-OSA ch-OSA (6 drops/d); Calcium (1,000 mg/d); Vitamin D (800 IU/d) Results may vary

The breakthrough in collagen! Collagen is essential for beautiful skin, hair and nails as well as healthy bones and joints. But starting at age 21, collagen diminishes 1% per year. By age 30, the signs become visible. For years, scientists searched for a method to give the human body the ability to regenerate its own collagen.

R2

Product Details

UPC / SKU 5 42501 039185 9
DSLD Entry Date 2017-08-22
Product Type Single Vitamin and Mineral
Form Liquid
Brand BioSil
DSLD ID 77113
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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