🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

10 mcg (50% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 100mg
UC-II standardized Cartilage
40 mg

Other Ingredients

Calcium Carbonate Cellulose Cellulose Coating Stearic Acid Croscarmellose Polydextrose Titanium Dioxide color Contains Less Than 2% of

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions For Adult Use: Take one (1) tablet per day preferably with food. As a reminder, discuss the supplements and medications you take with your health care providers.

1 per day

⚠️ Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

Keep out of reach of children.

Tamper Resistant: Do not use if blister seal is cut, torn or open.

Caution: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

🧪 Formulation Notes

This special joint health formula combines: UC-II Collagen A unique natural source of collagen that supports joint comfort. Joint Shield 5-Loxin Advanced Shows improved joint comfort in 7 days. Vitamin D3 An active & potent form of Vitamin D that helps support bone health.

Free of gluten and shellfish Non-GMO

Osteo Bi-Flex Ease is an easy-to-take mini-tab that’s 80% smaller than Osteo Bi-Flex One Per Day tablets, free of shellfish and gluten, and is completely non-GMO.

UC-II Collagen with Joint Shield

Additional Information

Free 7-day sample

#1 Pharmacist recommended brand 2016-2017 U.S. & World Report News Pharmacy Times

Not for resale

65718 B55388 01B

Store at room temperature and avoid excessive heat.

80% smaller tablet

Joint health Advanced triple action

Shows improved joint comfort within 7 days!

Actual size

Shows improved joint comfort in as little as 7 days, and with continued use, you could enjoy improved joint comfort over time.

America's #1 joint health brand

Manufacturer’s Coupon Expiration Date: 12/31/2019 Save $4 on 1 Osteo Bi-Flex 0030768400984 Consumer: This coupon good only on the purchase of product indicated. Any other use constitutes fraud. Limit one coupon per purchase. Consumer pays any sales tax. Void if copied, transferred, prohibited, taxed or restricted. Good only in USA, including U.S. Military Bases. Retailer: For payment of face value, plus 8¢ handling, send to Rexall Sundown C/O CMS, Dept. 30768, 1 Fawcett Drive, Del Rio, TX 78840. Coupon will be paid only if presented by an authorized retailer of our merchandise. Cash redemption value of 1/100 of one cent.

Based on Nielsen data for the 52 weeks ending September 24, 2016.

Product Details

DSLD Entry Date 2017-07-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 76786
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
View all evidence for Vitamin D →

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