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OPC

product on market Capsule HBC Protocols Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Oligomeric proanthocyanidins are researched for their antioxidant properties and potential to support cardiovascular health. Current evidence for these specific benefits is generally considered moderate. The ingredient profile maintains a high safety rating with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for OPC
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (284 products) 10 studies (A:0, B:4)

Other Ingredients

Brown Rice Flour
Claims

Label Claims — Verification

Unverified Structure/Function
Info

Product Information

Directions for Use

Directions For Use: As a food supplement, take 1 or 2 capsules with water daily, on an empty stomach, or as directed by a health professional.

Formulation Notes

Masquelier's 100% pure Oligomeric Proanthocyanidins 100 mg

Additional Information

This proven product can only be obtained through a specialized proprietary extraction process.

Substantiated by over 50 years of research and human studies, OPC maintains and promotes optimal circulatory and cardiovascular health. It is a powerful antioxidant that helps protect cells and tissues from free radical-initiated damage, providing superior cellular protection against various types of enzymatic attack as well. OPC has a unique ability to strengthen and rebuild collagen.

Masquelier’s OPC is the only grape seed/pine bark extract validated by French Ministry of Health

Metadata

Product Details

DSLD Entry Date2017-06-23
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandHBC Protocols
DSLD ID74944
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
2
Meta Analysis
2
Clinical Trial
1
Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023 PubMed DOI
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021 PubMed DOI
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011 PubMed DOI
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016 PubMed DOI
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021 PubMed DOI
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016 PubMed DOI
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009 PubMed DOI
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021 PubMed DOI
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition PubMed DOI
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies PubMed DOI
View all evidence for Grape Seed →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.