🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Label Data

2 Tablet(s) Serving Size
90 Servings
Other Combinations Product Type
20% Evidence Coverage

Supplement Facts — Evidence Check

10 mg (500% DV)
📊 4.3× RDA — above typical dose (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 10mg UL 11mg
Perna canaliculus
1000 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 600mg
📊 Market median: 1000.0mg (2 products)
This product: 400mg
N,N-Dimethylglycine HCl
200 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Vegetable Stearate Sodium Carboxymethylcellulose Silicon Dioxide Cinnamon (Cinnamomum cassia) oil Polyethylene Glycol Methylcellulose Titanium Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (74% of products) Nutrient (37% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 2 tablets, 3 times daily with food for 2 to 4 weeks, then reduce to 2 tablets once or twice daily with food.

⚠️ Warnings & Precautions

Warning: If pregnant or nursing, consult your healthcare practitioner before taking this product.

Warning: This product contains lead, a chemical known to the State of California to cause birth defects and other reproductive harm.

Keep out of reach of children.

Contains: Crustacean shellfish (shrimp and crab) and soy.

🧪 Formulation Notes

Perna mussels contain naturally occurring essential fatty acids, amino acids, polypeptides, chelated minerals, numerous enzymes, vitamins, nucleic acids (RNA and DNA), as well as glycosaminoglycans (GAGS).

Perna mussel & glucosamine msm

Made with Non-GMO ingredients

Contains: Crustacean shellfish (shrimp and crab) and soy.

Additional Information

Supports the health, comfort, flexibility and hydration of synovial fluid and connective tissues including joints, ligaments, tendons, cartilage and intervertebral discs.

Store in a cool, dry place.

To obtain product information or report a serious adverse event, call 1-800-874-9444.

0300365.180 1216B

Doctor formulated

Supports proper joint and connective tissue functions and comfort

Product Details

UPC / SKU 0 26664 33651 4
DSLD Entry Date 2017-06-23
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 74934
Data Updated 2026-04-11

Research Evidence

11 Research Sources
47 Avg Quality Score
7 Rct
2 Meta Analysis
1 Regulatory Source
C Trace elements and Alzheimer dementia in population-based studies: A bibliometric and meta-analysis
Meta Analysis Environmental pollution (Barking, Essex : 1987) 2023
C Proteins involved in iron metabolism in beef cattle are affected by copper deficiency in combination with high dietary manganese, but not by copper deficiency alone
Rct Journal of animal science 2010
C Reducing mineral usage in feedlot diets for Nellore cattle: II. Impacts of calcium, phosphorus, copper, manganese, and zinc contents on intake, performance, and liver and bone status
Rct Journal of animal science 2017
C Copper, Ceruloplasmin, Zinc, and Manganese Levels in Brain and Biological Fluids from Parkinson's Disease Patients: Systematic Review and Meta-Analysis
Meta Analysis Cells 2026
C Risedronate reverses bone loss in postmenopausal women with low bone mass: results from a multinational, double-blind, placebo-controlled trial. BMD-MN Study Group
Rct The Journal of clinical endocrinology and metabolism 2000
C Dietary Reference Intakes: Manganese
Regulatory Source IOM/NAM Dietary Reference Intakes 2000
C Vitamins and minerals intake adequacy in hematopoietic stem cell transplant: results of a randomized controlled trial.
Rct Bone marrow transplantation
C Collagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.
Rct Endocrine, metabolic & immune disorders drug targets
C Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study
Rct Military medicine 1999
C Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: A split-face, randomized trial.
Rct Dermatologic therapy
View all evidence for Manganese →

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