🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 20% of ingredients have research evidence
B Label Compliance Grade

Product Label

📸

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Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
20% Evidence Coverage

Supplement Facts — Evidence Check

300 mg
📊 Market median: 340.0mg (243 products) 📚 3 studies — no high-quality reviews
This product: 300mg
Lion's Mane
300 mg
Skullcap
200 mg
Lemon Balm (Melissa officinalis) leaf extract
100 mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 100mg

Other Ingredients

dried myceliated Brown Rice Pullulan Maltodextrin

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (86% of products) Nutrient (9% of products)

Target Groups

Adult (18 - 50 Years) Organic Gluten Free

Product Information

📋 Directions for Use

Directions For Use: As a dietary supplement, take 2 capsules once per day. Can be taken with food or on an empty stomach or as recommended by your healthcare advisor.

⚠️ Warnings & Precautions

Keep out of reach of children.

If you have a medical condition, are taking medications, or are pregnant or nursing, consult your healthcare professional before using this product.

🧪 Formulation Notes

Made with certified organic ingredients

Non-GMO verified ingredients

Made with organic mushrooms, skullcap, lemon balm & ashwagandha

Gluten free

Certified organic by the Washington State Department of Agriculture.

We use activated, dried, certified organic mushroom mycelium, with a full spectrum of constituents which are essential for supporting natural immunity.

Additional Information

Host Defense is the #1 best-selling mushroom brand in the U.S.: The highest quality and scientifically validated

Guaranteed, accurate identity of each mushroom

Identity guaranteed

Producer Certified organic Washington State Dept. of Agriculture

Non GMO Project Verified

Heat treated to proper temperature to ensure safety & bioavailabilty +200(0)F

Produced under the direct supervision of Paul Stamets, D.Sc. Proceeds help to save bees, trees, people & planet Bee friendly

Source: SPINScan natural/Natural products supermarkets > $2MM/Total US - Natural channel/Mushroom ingredient report/52 wks ending 9/04/2016

Promotes natural calm & tranquility

By including certified organic herbs that have been carefully selected to complement the health benefits of mushrooms, this marriage provides the best of both worlds. Like the dance of the sun and the moon, two kingdoms are paired together to provide the best possible functional food formula for promoting natural calm and tranquility

Feature Benefit Reishi Supports adrenal function Lion's mane Supports a calm and balanced mood Lemon balm Supports a peaceful emotional state Ashwaganda Promotes a healthy stress response Skullcap Promotes mental relaxation

Product Details

DSLD Entry Date 2017-05-24
Product Type Other Combinations
Form Capsule
DSLD ID 74180
Data Updated 2026-04-11

Research Evidence

6 Research Sources
60 Avg Quality Score
3 Meta Analysis
3 Rct
B Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors
Meta Analysis The Cochrane database of systematic reviews 2015
B Ganoderma lucidum (Reishi mushroom) for cancer treatment
Meta Analysis The Cochrane database of systematic reviews 2016
B Ganoderma lucidum (Reishi mushroom) for cancer treatment
Meta Analysis The Cochrane database of systematic reviews 2012
C Dynamic biomarkers indicate the immunological benefits provided by Ganoderma spore powder in post-operative breast and lung cancer patients
Rct Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2021
C Efficacy of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Supplementation on Psychological Stress and Selective Fitness Profile Parameters in Female College Students in West Bengal, India
Rct International journal of medicinal mushrooms 2024
C Preliminary Efficacy and Safety of Reishi & Privet Formula on Quality of Life Among Non-Small Cell Lung Cancer Patients Undergoing Chemotherapy: A Randomized Placebo-Controlled Trial
Rct Integrative cancer therapies 2020
View all evidence for Reishi →

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