🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Veg Capsule(s) Serving Size
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

100 mg
📊 Market median: 100.0mg (70 products)
Median 100.0mg This product: 100mg

Other Ingredients

Cellulose powder Cellulose Stearic Acid Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (81% of products) Nutrient (6% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 capsule 1 to 2 times daily on an empty stomach, or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Cautions/Interactions: Nattokinase may interact with anticoagulant and antiplatelet medications, including NSAIDs, warfarin, heparins, and clopidogrel. Consult your healthcare practitioner before taking this product if you are taking blood thinning or other medications, if you have ongoing bleeding/coagulation issues (including but not limited to: active ulcer, recent surgery/trauma, hemophilia), if you have a medical condition including uncontrolled high blood pressure (equal or higher to 200 mmHg/110mmHg), if you are planning a surgical procedure, or if you are pregnant/ nursing.

Contains soy.

Not manufactured with wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

Vegetarian/Vegan

Contains soy.

Not manufactured with wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients.

Contains no Vitamin K.

Do not eat freshness packet. Keep in bottle.

Additional Information

How It Works: Nattokinase is an enzyme isolated from Natto, a traditional Japanese fermented soy food that has been consumed for thousands of years for its numerous health promoting properties.* More recently, both clinical and non-clinical studies have demonstrated that Nattokinase can promote heart and circulatory health by helping to maintain normal blood fluidity.*

CODE P3140 V6

~ Cardiovascular health* ~ Helps maintain normal blood flow*

Natural color variation may occur in this product.

Product Details

UPC / SKU 7 07359 13140 8
DSLD Entry Date 2017-05-24
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 73284
Data Updated 2026-04-11

Research Evidence

4 Research Sources
45 Avg Quality Score
2 Rct
1 Other
1 Systematic Review
B Nattokinase Supplementation and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Systematic Review Reviews in cardiovascular medicine 2023
C Effects of nattokinase on blood pressure: a randomized, controlled trial
Rct Hypertension research : official journal of the Japanese Society of Hypertension 2008
C A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles
Rct Scientific reports 2015
D [A clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidaemia]
Other Zhonghua yi xue za zhi 2017
View all evidence for Nattokinase →

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