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Goldenseal Plus

product on market Capsule Vital Nutrients Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Goldenseal root and berberine are researched for their antimicrobial and anti-inflammatory properties. However, the overall evidence coverage for this specific combination is limited. These ingredients are generally considered safe for short-term use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Goldenseal Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsules
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Goldenseal root extract
200 mg
64 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)

Other Ingredients

Cellulose Vegetable Cellulose Capsule Leucine Silica
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Recommendations 1 or 2 capsules 2 to 4 times daily, or as directed by your healthcare professional.

Warnings & Precautions

Keep out of reach of children

Use only if seal is intact

Warning If pregnant, consult your physician before taking.

Formulation Notes

Excludes coatings, binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, sugar. Verified by independent testing.

Additional Information

Store sealed in a cool dry place

Raw materials and finished products are independently tested by U.S. labs. Learn more at vitalnutrients.net

REV. 1116

Metadata

Product Details

UPC / SKU6 93465 21711 5
DSLD Entry Date2017-03-24
Product TypeOther Combinations
FormCapsule
DSLD ID72003
Data Updated2026-04-11
Research

Research Evidence

98
Research Sources
55
Avg Quality
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 PubMed DOI
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019 PubMed DOI
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023 PubMed DOI
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024 PubMed DOI
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019 PubMed DOI
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.