Home/ Supplements/ 5 Htp/ L-5-HTP 100 mg

L-5-HTP 100 mg

product on market Capsule Vitabase Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Griffonia bean extract provides L-5-HTP, which has moderate evidence for supporting mood regulation. Vitamin B6 acts as a cofactor in serotonin synthesis, while Vitamin C supports general antioxidant functions. Research coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for L-5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical with Nutrients
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
250 mg (417% DV)
25 mg (1250% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Griffonia bean extract
102 mg

Other Ingredients

Gelatin May contain one or more of the following:
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, adults take one (1) capsule daily with meals, or as directed by a health care professional.

Warnings & Precautions

Keep out of reach of children.

Caution: Not for use by children under 18 years.

If pregnant or nursing, consult a physician before using this product.

Do not use while operating a motorized vehicle or heavy machinery.

Consult a physician before taking this product while using antidepressants or MAO-inhibiting medications.

Formulation Notes

Contains No Added sugar, salt, dairy, yeast, wheat, corn, soy, preservatives, artificial colors or flavors.

L-5-hydroxyTryptophan 100 mg, European

It provides optimal levels if naturally occurring L-5-hydroxyTryptophan.

Additional Information

Store in a cool, dry place and away from direct light.

QUALITY AND POTENCY GUARANTEED.

Vb

Our Standard Griffonia Extract is made under strict European quality standards which are comparable to Over-The-Counter drug standards in the US. It provides optimal levels if naturally occurring L-5-hydroxyTryptophan. Our L-5-HTP is formulated with important nutrients to optimize its effectiveness. Vitamin C and B-6 aid the conversion of tryptophan to serotonin in the body.

Metadata

Product Details

DSLD Entry Date2012-03-23
Product TypeBotanical with Nutrients
FormCapsule
DSLD ID7144
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
Compare

Similar Products

View all 5 Htp products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.