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D3 5000 IU

product on market Softgel Capsule Nature Made Safety: 60/100
60/100

Review before taking

  • Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin D3 is supported by strong evidence for maintaining bone health and supporting immune function. However, the evidence coverage for this specific profile is very limited. Due to the high dosage, potential concerns regarding toxicity or over-supplementation may exist.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D3: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a lower safety score because the amount of Vitamin D3 exceeds the recommended daily upper limit for safety.

Label

Product Label

Label for D3 5000 IU
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5000 IU (1250% DV)
Exceeds UL by 1.2× (UL: 0.1 mg) 608 studies (A:16, B:251)

Other Ingredients

Soybean Oil Gelatin Glycerin Water Corn Oil
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Dosage: Suggested Use: Take one softgel daily, with a meal.

Warnings & Precautions

Interactions: Caution: Use as directed by your health care professional. Do not take if you have kidney disease, hypercalemia (high blood calcium) or may have sensitivity to hypercalcemia (such as cancer, hyperparathyroidism, sarcoidosis or other granulomatous disorders), unless directed by your health care professional.

Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product. Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as: - Diminished drug effectiveness - Reduced supplement effectiveness - Impaired drug and/or supplement absorption

Contains: Soy

Formulation Notes

Contains: Soy

Additional Information

# 1 Pharmacist recommended

USP Dietary Supplement Verified

Ultra strength

D3 is the body's preferred form of vitamin D

Helps support bone, teeth, muscle and immune health

Metadata

Product Details

DSLD Entry Date2017-03-24
Product TypeVitamin
FormSoftgel Capsule
BrandNature Made
DSLD ID71376
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.