🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Yellow Capsule(s) Serving Size
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Levagen Palmitic Acid Monoethanolamide
300 mg
Joint Comfort Proprietary Blend
250 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 100mg

Other Ingredients

Cellulose Gelatin Magnesium Stearate Polysorbate 80 Povidone Stearic Acid

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily.

⚠️ Warnings & Precautions

Warning: Do not use if pregnant, nursing or allergic or contraindicated to aspirin. If you are taking aspirin or blood thinning or other medication, or have a medical condition, consult your physician before using this product.

Warning: Do not use if pregnant, nursing or allergic or contraindicated to aspirin. If you are taking aspirin or blood thinning or other medication, or have a medical condition, consult your physician before using this product.

Discontinue use two weeks prior to surgery.

🧪 Formulation Notes

No sugar, no artificial colors, no artificial flavors, no preservatives, no wheat, gluten free, no dairy, yeast free.

With four powerful, clinically studied ingredients, TriFlex Daily Pack is our most comprehensive program to support improved joint comfort, flexibility and function. It includes: Comfort, Function & Flexibility support - Features a blend of natural plant extracts that is clinically shown to provide 30% improvement in flexibility and 19% improvement in joint function in as few as 30 days. Plus it contains Levagen, which is clinically studied to support the body's natural anti-inflammatory response. Also includes turmeric.

Provides clinical-strength doses of our joint comfort blend, Levagen, glucosamine and chondroitin - plus EPA

Additional Information

Gf Gluten free

Comfort, Function & Flexibility

Store in a cool, dry place.

Our quality commitment to you Since 1935, our mission has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you're not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we'll either refund your money or find you a replacement product that is right for you.

In a 12 week multi-center, randomized, double-blind, placebo-controlled study of 60 adults, subjects taking 250 mg/day of the Joint Comfort Proprietary Blend showed a significant 29.8% improvement in joint flexibility and a 19.4% improvement in joint function in 30 days compared to subjects on placebo.

New!

Promotes joint health

Comprehensive program with clinically proven ingredients Supports improved joint comfort, flexibility and function, and the body's natural anti-inflammatory response

CODE 303212 LQG

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Actual size

Product Details

DSLD Entry Date 2017-01-25
Product Type Other Combinations
Form Capsule
Brand GNC TriFlex
Bundle Daily Pack
DSLD ID 69625
Data Updated 2026-04-11

Research Evidence

311 Research Sources
54 Avg Quality Score
121 Systematic Review
98 Meta Analysis
70 Rct
16 Clinical Trial
2 Other
1 Narrative Review
1 Openfda Safety
A The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis
Meta Analysis Bioscience reports 2021
B Curcumin for depression: a meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2020
B Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2024
B Complementary and Alternative Medicine Therapies for Psoriasis: A Systematic Review
Meta Analysis JAMA dermatology 2018
B Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review
Systematic Review Critical reviews in food science and nutrition 2022
B Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2024
B The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis
Meta Analysis Complementary therapies in medicine 2021
B Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy on Candida spp.-A Systematic Review
Systematic Review International journal of molecular sciences 2024
B Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis BMC complementary medicine and therapies 2025
B Natural Products in Alzheimer's Disease: A Systematic Review of Clinical Trials and Underlying Molecular Mechanisms
Systematic Review International journal of molecular sciences 2025
View all evidence for Curcumin →

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