Glucosamine Sulfate 500 mg by Whole Foods — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Capsule(s) Serving Size

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Glucosamine Sulfate

500 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 500mg

Other Ingredients

Rice powder Magnesium Stearate Gelatin

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Take 1 capsule, three times daily with meals.

⚠️ Warnings & Precautions

Tamper evident; use only if seal is intact.

Allergen Information: Contains shellfish (shrimp, crab) ingredients. Good manufacturing practices used to segregate in a facility that also processes milk, egg, fish, tree nut, wheat and soy ingredients.

Note: Do not take this if you are allergic to shellfish.

If you are diabetic, pregnant or lactating, consult your health care practitioner before using this product.

Keep out of reach of children.

🧪 Formulation Notes

Allergen Information: Contains shellfish (shrimp, crab) ingredients.

Contains no artificial colors, flavors or preservatives.

Additional Information

Please recycle this bottle.

1 PETE Please recycle this bottle

Post Consumer Recycled Bottle 100% PCR

Boost joint function

Store in a cool, dry place.

228098 401228098-D

Product Details

UPC / SKU 0 99482 28098 7

DSLD Entry Date 2016-06-24

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Whole Foods

DSLD ID 60808

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →