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Silymarin 100 mg

product on market Capsule Life Extension Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Silymarin is researched for its potential to support liver health and protect hepatocytes, though evidence for general use is often considered limited. The Citrus Bioflavonoid Complex provides antioxidant support to help neutralize free radicals. Overall, clinical evidence for this specific combination is sparse.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Silymarin 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)

Other Ingredients

Microcrystalline Cellulose Vegetable Cellulose Silica Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) capsule one to three times daily with or without food, or as recommended by a healthcare practitioner.

Warnings & Precautions

WARNINGS: KEEP OUT OF REACH OF CHILDREN.

DO NOT EXCEED RECOMMENDED DOSE.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Additional Information

Store tightly closed in a cool, dry place.

Q01684C

Supports a Healthy Liver

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Scan for product info

Do not purchase if outer seal is broken or damaged.

Q01684C

Metadata

Product Details

UPC / SKU7 37870 16845 4
DSLD Entry Date2016-05-22
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandLife Extension
DSLD ID59213
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.