PalmettoGuard by Life Extension — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Softgel(s) Serving Size

Botanical with Nutrients Product Type

14% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 {Calories}

Total Fat

0.5 Gram(s) (1% DV)

Cholesterol

Saw Palmetto CO2 extract

320 mg

📊 Market median: 320.0mg (426 products) 📚 24 studies (Tier A: 0, B: 5)

This product: 320mg

Beta-Sitosterol

90 mg

Boron

3 mg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 3mg UL 20mg

Rosemary extract

400 mcg

Other Ingredients

Pumpkin seed Oil Gelatin Glycerin Sunflower Lecithin purified Water Caramel color

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (83% of products) Nutrient (17% of products)

Target Groups

Adult Male (18-50 Years)

Product Information

📋 Directions for Use

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) softgel daily with or without food, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

WARNINGS: ~ KEEP OUT OF REACH OF CHILDREN.

~ DO NOT EXCEED RECOMMENDED DOSE. ~ Do not purchase if outer seal is broken or damaged.

~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

🧪 Formulation Notes

PalmettoGuard Saw Palmetto with Beta-Sitosterol

One-Per-Day Prostate Support*

Additional Information

Q01789B

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Store tightly closed in a cool, dry place.

Product Details

UPC / SKU 7 37870 17893 4

DSLD Entry Date 2016-04-22

Product Type Botanical with Nutrients

Form Softgel Capsule

Brand Life Extension

DSLD ID 59206

Data Updated 2026-04-11

Research Evidence

35 Research Sources

52 Avg Quality Score

15 Meta Analysis

11 Systematic Review

7 Rct

1 Narrative Review

1 Openfda Safety

B Serenoa repens for benign prostatic hyperplasia

Meta Analysis The Cochrane database of systematic reviews 2009

PubMed DOI

B Serenoa repens for benign prostatic hyperplasia

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI

B Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement: A systematic review and meta-analysis

Meta Analysis Investigative and clinical urology 2021

PubMed DOI

B Clinical Efficacy of Serenoa repens Versus Placebo Versus Alpha-blockers for the Treatment of Lower Urinary Tract Symptoms/Benign Prostatic Enlargement: A Systematic Review and Network Meta-analysis of Randomized Placebo-controlled Clinical Trials

Systematic Review European urology focus 2021

PubMed DOI

B Non-hormonal treatment for male infertility: the potential role of Serenoa repens, selenium and lycopene

Systematic Review European review for medical and pharmacological sciences 2019

PubMed DOI

B Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis

Meta Analysis American journal of men's health 2020

PubMed DOI

B Serenoa repens monotherapy for benign prostatic hyperplasia (BPH): an updated Cochrane systematic review

Systematic Review BJU international 2012

PubMed DOI

B Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis