🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

6 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Calories
15 {Calories}
Total Carbohydrates
1 g (1% DV)
Protein
2 g (4% DV)
Sodium
60 mg (2% DV)
📊 Market median: 60.0mg (94 products) 📚 13 studies (Tier A: 0, B: 7)
This product: 3000mg
📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)
This product: 200mg

Other Ingredients

Dicalcium Phosphate Croscarmellose Sodium

Label Claims — Verification

All Other
Structure/Function
All Other (96% of products) Structure/Function (81% of products) Nutrient (19% of products) No Claim (3% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

DIRECTIONS: Take 6 tablets per day with meals.

⚠️ Warnings & Precautions

Caution: If pregnant or nursing, consult your physician prior to use.

Bottle has printed seal under cap for your protection.

🧪 Formulation Notes

Gluten free.

No artificial flavors, sweeteners, or preservatives added.

Additional Information

CARDIO HEALTH

Cholesterol Regulation Complex is a unique blend of natural ingredients that helps retain normal cholesterol levels and also increase HDL (good) cholesterol levels by up to 37% within three months.* It helps inhibit absorption of dietary cholesterol and does not interrupt Coenzyme Q10 production.* N-acetylcysteine supports the body's natural antioxidant defenses, which help prevent LDL oxidation.*

Helps Retain Normal Cholesterol Levels*

NG348A Item #20648

PHYTOPEPTIDES, PHOSPHOLIPIDS, & N-ACETYLCYSTEINE

Promotes Cardiovascular Health*

100% SHAKLEE GUARANTEE

Product Details

DSLD Entry Date 2012-01-25
Product Type Other Combinations
Form Tablet or Pill
Brand Shaklee
DSLD ID 5065
Data Updated 2026-04-11

Research Evidence

41 Research Sources
51 Avg Quality Score
19 Rct
13 Meta Analysis
9 Clinical Trial
B N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication
Meta Analysis The Cochrane database of systematic reviews 2019
B Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial
Rct Nature communications 2024
B N-acetylcysteine for non-paracetamol (acetaminophen)-related acute liver failure
Meta Analysis The Cochrane database of systematic reviews 2020
B Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis
Meta Analysis European respiratory review : an official journal of the European Respiratory Society 2015
B A randomised controlled trial of a mitochondrial therapeutic target for bipolar depression: mitochondrial agents, N-acetylcysteine, and placebo
Rct BMC medicine 2019
B Efficacy of N-acetylcysteine for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024
B Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates
Meta Analysis The Cochrane database of systematic reviews 2006
B N-acetylcysteine as an adjunctive treatment for bipolar depression: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Bipolar disorders 2021
B N-acetylcysteine as an adjunctive treatment for bipolar depression and major depressive disorder: a systematic review and meta-analysis of double-blind, randomized placebo-controlled trials
Meta Analysis Psychopharmacology 2020
B N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis/Pre-COPD: Distinct Meta-analyses
Meta Analysis Archivos de bronconeumologia 2024
View all evidence for Nac →

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