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Ciruplex

product on market Tablet or Pill Sunshine Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 12% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The primary components consist of basic macronutrients, including proteins and carbohydrates, which provide essential energy and structural support for the body. There is strong evidence supporting the role of these nutrients in maintaining general health. However, the overall evidence coverage for this specific formulation is very limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Ciruplex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
45
Servings
Botanical
Product Type
12%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 {Calories} (6% DV)
Total Fat
1.04 mg (2% DV)
Sodium
0.3 mg
Total Carbohydrates
1 Gram(s)
Proteins
0.2 mg (1% DV)
dried Plum extract
300 mg
400 mg
Market median: 1000.0mg (212 products) 12 studies (A:0, B:3)
Cascara Sagrada
300 mg

Other Ingredients

Di-Calcium Phosphate Microcrystalline Cellulose Stearic Acid Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults and children 15 years or age and over, take 2 tablets once or twice a day with a glass of water or juice.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

With dried plums, flaxseed & Cascara sagrada

Ciruplex has been formulated for those who suffer occasional constipation.

Ciruplex does not contain Senna, to prevent side effects.

A natural gentle laxative with dried plums

Additional Information

For those who suffer occasional constipation*

Made in U.S.A.

Metadata

Product Details

UPC / SKU7 89939 10140 7
DSLD Entry Date2015-08-25
Product TypeBotanical
FormTablet or Pill
BrandSunshine Naturals
DSLD ID49782
Data Updated2026-04-11
Research

Research Evidence

20
Research Sources
49
Avg Quality
7
Rct
7
Clinical Trial
6
Meta Analysis
B Effects of flaxseed supplements on blood pressure: A systematic review and meta-analysis of controlled clinical trial
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2016 PubMed DOI
B The effect of flaxseed supplementation on anthropometric indices, blood pressure, and lipid profile in diabetic patients: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials
Meta Analysis Diabetes & metabolic syndrome 2025 PubMed DOI
B Effect of flaxseed supplementation on blood pressure: a systematic review, and dose-response meta-analysis of randomized clinical trials
Meta Analysis Food & function 2023 PubMed DOI
C The effect of flaxseed oil consumtion on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytotherapy research : PTR 2022 PubMed DOI
C Flaxseed consumption may reduce blood pressure: a systematic review and meta-analysis of controlled trials
Meta Analysis The Journal of nutrition 2015 PubMed DOI
C A comparison between the effects of flaxseed oil and fish oil supplementation on cardiovascular health in type 2 diabetic patients with coronary heart disease: A randomized, double-blinded, placebo-controlled trial
Rct Phytotherapy research : PTR 2019 PubMed DOI
C Supplementation of Olive Oil and Flaxseed Oil on Blood Pressure and Inflammation in Healthy and At-Risk Adults: A Systematic Literature Review and Meta-Analysis
Meta Analysis Current hypertension reviews 2024 PubMed DOI
C Dietary Flaxseed Reduces Central Aortic Blood Pressure Without Cardiac Involvement but Through Changes in Plasma Oxylipins
Rct Hypertension (Dallas, Tex. : 1979) 2016 PubMed DOI
C Effect of Food with Low Enrichment of N-3 Fatty Acids in a Two-Month Diet on the Fatty Acid Content in the Plasma and Erythrocytes and on Cardiovascular Risk Markers in Healthy Young Men.
Rct Nutrients PubMed DOI
C Enterolignan Production in a Flaxseed Intervention Study in Postmenopausal US Women of African Ancestry and European Ancestry.
Rct Nutrients PubMed DOI
View all evidence for Flaxseed →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.