🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Label Data

1 Softgel(s) Serving Size
60 Servings
Non-Nutrient/Non-Botanical Product Type
25% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 {Calories}
Calories from Fat
10 {Calories}
Total Fat
1 Gram(s)
100 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 100mg UL 1200mg

Other Ingredients

Safflower Oil Gelatin Glycerin Beeswax Lecithin purified Water Polyglycerol Fatty Acid Esters Caramel color

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (87% of products) Nutrient (13% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Dosage and Use ~ Take on softgel with food once or twice daily, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Contains soybeans.

Warnings: ~ Keep out of reach of children

~ Do not exceed recommended dose ~ Do not purchase if outer seal is broken or damaged.

~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

🧪 Formulation Notes

Contains soybeans.

This product contains no milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, corn, rice. Contains No sugar and no artificial sweeteners, flavors, or preservatives.

Additional Information

100 mg 60 softgels.

The mitochondria are the cells energy powerhouses, and coenzyme Q10 (CoQ10) is an essential component of healthy mitochondrial function. CoQ10 is required to convert the energy unlocked from fats and sugars into usable cellular energy. Yet, the body's production of CoQ10 declines significantly with advancing age. 47 With an ample amount of CoQ10, mitochondria can can work most efficiently throughout the entire body-including the most densely populated area, the heart. 48 CoQ10 is also a potent antioxidant helping protect proteins, and DNA of mitochondria from oxidation and supporting mitochondria function.45 Most people are supplementing with CoQ10 than ever before. One reason is increased awareness that "statin" drugs used to lower LDL and cholesterol deplete CoQ10 levels in the blood, and possibly the tissues.49,50 What most doctors don't know, however, is that normal aging may result in more of a reduction in CoQ10 than taking statins. For example, while statin drugs have been shown to reduce plasma CoQ10 by nearly 40%,51 the aging process reduces CoQ10 levels in the heart muscle wall by 72%. 52 What is particularly frightening is the deficit caused by the dual effects of aging 53 and statin drug use that can result in severe depletion of cellular vitality.51 CoQ10 is notoriously difficult to absorb. When it comes to choosing a CoQ10 supplement, the primary factor is how many swallowed milligrams actually make it into your bloodstream. A recent study showed that in seriously ill patients, conventional ubiquinone CoQ10 was hardly detectable in the blood whereas ubiquinol resulted in significant blood level increases and subsequent clinical improvements. Scientific studies show that ubiquinol absorbs up to 8 times greater that ubiquinone, and higher levels of ubiquinol remain in the blood far longer than ubiquinone. In studies measuring exercise-induced fatigue, ubiquinol was 90% more effective that ubiquinone. In middle-aged mice, ubiquinol was shown to be 40% more effective in slowing measurements of aging compaed to ubiquinone. 54 Life Extension offers the highly bioavailable ubiquinol form of CoQ10 in a patented delivery system with a superior absorption level. 55 References Ratings based on results of the 2013 CosumerLab.com. Survey of Supplement Users. More information at www.consumerlab.com

The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.

{Softgel}

#1 Rated

Item #01226

Product Details

DSLD Entry Date 2015-08-25
Product Type Non-Nutrient/Non-Botanical
Form Softgel Capsule
DSLD ID 49221
Data Updated 2026-04-11

Research Evidence

202 Research Sources
55 Avg Quality Score
86 Meta Analysis
62 Systematic Review
28 Rct
17 Clinical Trial
4 Regulatory Source
2 Other
1 Narrative Review
1 Openfda Safety
A Coenzyme Q10 for heart failure
Meta Analysis The Cochrane database of systematic reviews 2021
A Cardioprotective interventions for cancer patients receiving anthracyclines
Meta Analysis The Cochrane database of systematic reviews 2011
A Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis
Meta Analysis BMJ open 2021
A Effects of coenzyme Q10 supplementation on statin-induced myopathy: a meta-analysis of randomized controlled trials
Meta Analysis Irish journal of medical science 2022
B Cardioprotective interventions for cancer patients receiving anthracyclines
Meta Analysis The Cochrane database of systematic reviews 2008
B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Meta Analysis The Cochrane database of systematic reviews 2016
B Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Meta Analysis Reproductive sciences (Thousand Oaks, Calif.) 2023
B Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials
Meta Analysis International journal of molecular sciences 2020
B Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis
Meta Analysis Journal of nutritional science 2025
B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Meta Analysis The Cochrane database of systematic reviews 2009
View all evidence for Coq10 →

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