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Kava Kava 400 mg

product on market Capsule Natural Factors Stress-Relax Safety: 60/100
60/100

Review before taking

  • Kavapure(R) Kava Kava (Piper methysticum) extract: 400mg is 1.6× the Tolerable Upper Intake Level (250mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Kava Kava extract is supported by moderate evidence for reducing anxiety and promoting relaxation. However, the safety score indicates potential concerns, particularly regarding liver toxicity. Users should exercise caution due to these reported adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Kavapure(R) Kava Kava (Piper methysticum) extract: 400mg is 1.6× the Tolerable Upper Intake Level (250mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 400mg of Kava Kava, which exceeds the recommended daily upper limit of 250mg.

Label

Product Label

Label for Kava Kava 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 1.6× (UL: 250 mg) 15 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose Vegetarian Capsule Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: 1 capsule per day or as directed by a health professional.

Warnings & Precautions

Keep out of the reach of children.

Cautions: Consult a health professional prior to use if you have had liver problems, frequently use alcoholic beverages, or are taking any medication.

Stop use and consult a health professional if you develop symptoms that may signal liver problems (e.g., unexplained fatigue, abdominal pain, loss of appetite, fever, vomiting, dark urine, pale stools, yellow eyes or skin).

Not for use by persons under 18 years of age, or by pregnant or breastfeeding women.

Not for use by persons under 18 years of age, or by pregnant or breastfeeding women.

Not for use with alcoholic beverages. Excessive use or use with products that cause drowsiness may impair your ability to operate a vehicle or heavy equipment. Kava kava should NOT be taken on a daily basis for more than four weeks without consulting a health professional.

Sealed for your protection. Do not use if seal is broken.

Formulation Notes

Kavapure is standardized to 30% kavalactones, the active constituents in kava kava.

Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

30% KAVALACTONES

Additional Information

isura(TM)

NON-GMO · MASS SPEC -Documentation -Lab Tested

Kava kava is an herb that has been used traditionally in Polynesian cultures for centuries. Kava kava helps calm occasional anxiety, stress, and restlessness, and supports healthy sleep.*

Expert sourcing and extraction methods utilized by Kavapure maximizes the quality and consistency of the active ingredients, ensuring the highest possible bioavailability. Kavapure is the highest quality kava kava on the market. The safety and efficacy of kava have been proven through scientific research and clinical studies.*

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

For freshness, store in a cool, dry place.

PROMOTES RELAXATION & A SENSE OF CALM*

kavapure(R)

PRODUCT OF CANADA

R0

Purity & Potency Guaranteed

Recyclable container and label.

Metadata

Product Details

UPC / SKU0 68958 02851 4
DSLD Entry Date2015-07-24
Product TypeBotanical
FormCapsule
DSLD ID47709
Data Updated2026-04-11
Research

Research Evidence

19
Research Sources
48
Avg Quality
8
Rct
5
Systematic Review
4
Meta Analysis
2
Clinical Trial
B Kava extract for treating anxiety
Meta Analysis The Cochrane database of systematic reviews 2003 PubMed
B Kava for Generalized Anxiety Disorder: A Review of Current Evidence
Meta Analysis Journal of alternative and complementary medicine (New York, N.Y.) 2018 PubMed DOI
B Kava extract for treating anxiety
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Kava extract for treating anxiety
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The effectiveness and safety of Kava Kava for treating anxiety symptoms: A systematic review and analysis of randomized clinical trials
Systematic Review Complementary therapies in clinical practice 2018 PubMed DOI
C Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study
Rct The Australian and New Zealand journal of psychiatry 2020 PubMed DOI
C Kava and St. John's Wort: current evidence for use in mood and anxiety disorders
Systematic Review Journal of alternative and complementary medicine (New York, N.Y.) 2009 PubMed DOI
C Neuroimaging Insights: Kava's (Piper methysticum) Effect on Dorsal Anterior Cingulate Cortex GABA in Generalized Anxiety Disorder.
Rct Nutrients PubMed DOI
C The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava
Meta Analysis Annals of internal medicine 2002 PubMed
C Efficacy of kava extract for treating anxiety: systematic review and meta-analysis
Meta Analysis Journal of clinical psychopharmacology 2000 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.