Formula #1 OC-Classic With Fresh Royal Jelly by GPi — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
25% of ingredients have research evidence

B Label Compliance Grade

Product Label

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Label Data

1 tsp Serving Size

48 Servings

Other Combinations Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Calories

18 {Calories}

Total Carbohydrates

5 Gram(s) (2% DV)

Vitamin C

175 mg (290% DV)

Vitamin B12

2 mcg (35% DV)

✅ Within RDA (0.8× RDA of 0.0024 mg) 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.002mg

Other Ingredients

Honey Royal Jelly Vitamin C Honeybee Pollen Disodium EDTA Magnesium Chloride fortified with Vitamin B12

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (58% of products) Nutrient (21% of products) Qualified Health (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Take one teaspoon twice daily.

⚠️ Warnings & Precautions

Caution: Consult your physician prior to using this product if you are pregnant, nursing, or have any pre-existing medical conditions.

Keep out of reach of children.

Do not purchase if seal is broken.

🧪 Formulation Notes

The liquid form of Formula #1 is Vitamin Direct's original cardiovascular formulation. Loaded with natural sources of vitamins B5, B6, and B12 along with vitamin C and chelating agents like royal jelly and EDTA, it helps support the cardiovascular and immune systems.

Additional Information

Note: The color, taste, and texture of this product may vary due to its natural ingredients and/or seasonal changes.

Protect from heat, light and moisture. Store at 59-86(0)F (15-30(0)C).

GPi

Made in the USA

0512149100543 B

Formula #1 OC-Classic is recommended by chelating physicians and practitioners throughout the USA.

Item #100843 051214/9100843B

Product Details

DSLD Entry Date 2015-07-24

Product Type Other Combinations

Form Liquid

Brand GPi

DSLD ID 47444

Data Updated 2026-04-11

Research Evidence

10 Research Sources

42 Avg Quality Score

5 Rct

4 Other

1 Meta Analysis

B Royal jelly for management of postmenopausal symptoms: a systematic review and meta-analysis

Meta Analysis Menopause (New York, N.Y.) 2026

PubMed DOI

C A Randomized, Double-Blind Comparison Study of Royal Jelly to Augment Vascular Endothelial Function in Healthy Volunteers

Rct Journal of atherosclerosis and thrombosis 2022

PubMed DOI

C Apitherapy with Royal Jelly and Green Propolis EPP-AF® Improves Cardiovascular Risk Markers in Patients Undergoing Hemodialysis

Rct Toxins 2025

PubMed DOI

C Effect of Protease-Treated Royal Jelly Extract on Facial Wrinkles: A Placebo-Controlled, Double-Blind, Parallel-Group Study

Rct Journal of cosmetic dermatology 2025

PubMed DOI

C Royal jelly plus coenzyme Q10 supplementation improves high-intensity interval exercise performance via changes in plasmatic and salivary biomarkers of oxidative stress and muscle damage in swimmers: a randomized, double-blind, placebo-controlled pilot trial

Rct Journal of the International Society of Sports Nutrition 2022

PubMed DOI

C The effect of oral royal jelly administration on skin barrier function: a double-blind randomized placebo-controlled trial

Rct European journal of dermatology : EJD 2018

PubMed DOI

C Major royal jelly proteins prevents NAFLD by improving mitochondrial function and lipid accumulation through activating the AMPK / SIRT3 pathway in vitro

Other Journal of food science 2021

PubMed DOI

D Royal jelly reduces the serum glucose levels in healthy subjects

Other Journal of medicinal food 2009

PubMed DOI

D Greek-origin royal jelly improves the lipid profile of postmenopausal women

Other Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016

PubMed

D Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production

Other Journal of medicinal food 2011

PubMed DOI

View all evidence for Royal Jelly →