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Glucosamine Chondroitin Complex Plus MSM

product on market Tablet or Pill 21st Century Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 43% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine HCl and chondroitin are supported by moderate evidence for managing joint health and reducing discomfort. Vitamin D3 plays a key role in maintaining bone density and supporting immune function. These ingredients are generally well-tolerated, contributing to the product's high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Glucosamine Chondroitin Complex Plus MSM
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
40
Servings
Other Combinations
Product Type
43%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 {Calories}
Total Carbohydrates
2 Gram(s) (1% DV)
2000 IU (500% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
Sodium
20 mg (1% DV)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Proprietary Blend
325 mg
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)

Other Ingredients

Cellulose Stearic Acid Croscarmellose Sodium Polyvinyl Alcohol Titanium Dioxide Magnesium Stearate Talc Artificial colors PEG
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take up to two (2) tablets daily after meals or as directed by your healthcare provider. Do not exceed recommended dosage. Individual results may vary.

Warnings & Precautions

Warning: Consult a healthcare provider prior to use if: pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Contains shellfish (shrimp, crab, crayfish) ingredients.

WARNING:IF YOU ARE DIABETIC, CONSULT YOUR PHYSICIAN BEFORE USING THIS PRODUCT.

If you have a Shellfish allergy please consult your physician before using this product.

Formulation Notes

No added Sugar, Artificial Flavors or Preservatives. Gluten Free.

ADVANCED TRIPLE STRENGTH + VITAMIN D3

Contains shellfish (shrimp, crab, crayfish) ingredients.

Plus the added Vitamin D3 supports bone strength and your immune system.

Additional Information

Store at room temperature.

GUARANTEED QUALITY LABORATORY TESTED

501191-1014

+Osteo Bi-Flex(R) Triple Strength+D is a registered trademark of Rexall Sundown, Inc., Boca Raton, FL 33487 USA

Many recent scientific studies have shown the effectiveness of taking supplements with the proper combination of Glucosamine HCI and Chondroitin Sulfate.* Theses compounds found in the soft cartilage, tendons and synovial fluid, are essential to the healthy functioning of tendons and joints, especially with advancing age.* Glucosamine & Chondroitin Complex Triple Strength + Vitamin D3 combines there two nutritional elements in the proper amounts for your effective use.*

2 PER DAY

Metadata

Product Details

UPC / SKU7 40985 27707 2
DSLD Entry Date2015-03-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID43632
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.