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MSM & Glucosamine

product on market Capsule Nature's Bounty Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine sulfate and MSM are researched for their roles in supporting joint health and cartilage maintenance. Evidence for their efficacy in reducing joint discomfort is generally considered moderate. These ingredients are typically well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for MSM & Glucosamine
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
45
Servings
Non-Nutrient/Non-Botanical
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

MSM
500 mg
Market median: 1000.0mg (2 products)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)

Other Ingredients

Dicalcium Phosphate Gelatin Magnesium Silicate Vegetable Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: For adults, take two (2) capsules three times daily, preferably with meals.

Warnings & Precautions

Keep out of reach of children.

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Discontinue use and consult your doctor if any adverse reactions occur.

Do not use if seal under cap is broken or missing.

Formulation Notes

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast. Sodium Free.

Additional Information

Store in a cool, dry place.

FOR EASY SWALLOWING

Helps Promote Healthy Joint and Cartilage*

MSM and Glucosamine is a combination of two popular supplements that play a role in the maintenance of joint cartilage.* MSM is an organic source of sulfur, a mineral that is vital in the formation of collagen, connective tissue, and healthy joint cartilage.* Research studies show that Glucosamine supports joint health.* Both Glucosamine and MSM help support your joints so you can enjoy your most productive years.*

Prod. No. 20932 07F B20930

(recycle) Healthy you Healthy earth

LABORATORY TESTED GUARANTEED QUALITY

NATURE'S BOUNTY(R)

Metadata

Product Details

UPC / SKU0 74312 20932 1
DSLD Entry Date2011-12-23
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID4117
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.