GI-Zyme

product on market Capsule Mannatech Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The product contains enzyme and herbal blends designed to support digestion and nutrient absorption. Research on these specific proprietary combinations is limited, though individual digestive enzymes generally show moderate evidence for improving gastrointestinal function. Beet fiber provides prebiotic support, but overall clinical evidence for this specific formulation is minimal.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for GI-Zyme
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Botanical with Nutrients
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Proprietary Phase 1 Enzyme Blend
96 mg
Proprietary Phase 2 Enzyme Blend
70 mg
Proprietary Herbal Blend
150 mg
44 mg
Market median: 100.0mg (1 products) 42 studies (A:1, B:15)

Other Ingredients

Vegetable Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Adult Use: Take one capsule before each meal.

Warnings & Precautions

WARNING: If you are pregnant, nursing, taking medication, have a health condition, or are planning a medical procedure, consult your health professional before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Do not use if inner seal is missing or broken.

Keep out of reach of children.

Additional Information

GI-ZYME

GI-Zyme capsules can help improve the level of digestion and may help ensure maximum levels of nutrient absorption.*

M(SM)

Keep bottle tightly closed.

DIGESTIVE ENZYME

SUPPORTS DIGESTIVE ABSORPTION*

Store in a cool, dry place.

Product Number 13201 US.13201.24.006

Metadata

Product Details

DSLD Entry Date2014-06-25
Product TypeBotanical with Nutrients
FormCapsule
DSLD ID34835
Data Updated2026-04-11
Research

Research Evidence

120
Research Sources
51
Avg Quality
47
Clinical Trial
38
Rct
20
Meta Analysis
13
Systematic Review
2
Cochrane Review
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Prebiotics for induction and maintenance of remission in ulcerative colitis
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
A Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Probiotics for management of functional abdominal pain disorders in children
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis
Meta Analysis The American journal of clinical nutrition 2018 PubMed DOI
B Effect of psyllium (Plantago ovata) fiber on LDL cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoprotein B: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis The American journal of clinical nutrition 2018 PubMed DOI
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Prebiotics, probiotics, fermented foods and cognitive outcomes: A meta-analysis of randomized controlled trials
Meta Analysis Neuroscience and biobehavioral reviews 2020 PubMed DOI
B Synbiotics, prebiotics and probiotics for people with chronic kidney disease
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Effects of Prebiotics and Probiotics on Symptoms of Depression and Anxiety in Clinically Diagnosed Samples: Systematic Review and Meta-analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025 PubMed DOI
View all evidence for Prebiotics →
Compare

Similar Products

View all Prebiotics products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.