Oregon Grape 400 mg
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
A
Label Compliance Grade
Product Label
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Label Data
2 Capsule(s)
Serving Size
50
Servings
Botanical
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
800 mg
📊 Market median: 500.0mg (234 products)
📚 95 studies (Tier A: 0, B: 35)
Other Ingredients
Cellulose
Diatomaceous Earth
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (100% of products)
Structure/Function (86% of products)
Nutrient (4% of products)
Target Groups
Adult (18 - 50 Years)
Women (not pregnant or lactating)
Gluten Free
Dairy Free
Sugar Free
Product Information
📋 Directions for Use
Directions: For adults, take two (2) capsules daily, more if needed.
⚠️ Warnings & Precautions
As a reminder, discuss the supplements and medications you take with your health care providers. Warning: Not intended for use by pregnant or nursing women. If you are taking any medications, consult your doctor before use.
Keep out of reach of children.
🧪 Formulation Notes
Contains no: Chemical Fillers or Binders, Artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.
From a GMP Facility
Berberis aquifolium
Additional Information
Store in a dry place and avoid excessive heat
Product Details
DSLD Entry Date
2025-09-25
Product Type
Botanical
Form
Capsule
Brand
Signature Supplements
DSLD ID
338879
Data Updated
2026-04-11
Research Evidence
98
Research Sources
55
Avg Quality Score
48
Systematic Review
39
Meta Analysis
4
Rct
4
Clinical Trial
1
Other
1
Narrative Review
1
Openfda Safety
B
Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
B
Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
B
Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
B
Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
B
Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
B
The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
B
Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
B
Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
B
Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
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