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Kava-Kava 400 mg

product on market Capsule Signature Supplements Safety: 60/100
60/100

Review before taking

  • Kava Kava Root Extract: 800mg is 3.2× the Tolerable Upper Intake Level (250mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Kava kava root extract is supported by moderate evidence for reducing symptoms of anxiety. However, the safety score indicates potential concerns, particularly regarding hepatotoxicity and liver health. Users should be aware of these risks when considering supplementation.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Kava Kava Root Extract: 800mg is 3.2× the Tolerable Upper Intake Level (250mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 800mg of Kava Kava Root Extract, which is over three times the recommended upper limit for daily intake.

Label

Product Label

Label for Kava-Kava 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
50
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 3.2× (UL: 250 mg) 15 studies (A:0, B:5)

Other Ingredients

Cellulose Diatomaceous Earth
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take two (2) capsules daily, more if needed.

Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers Warning: Pregnant or lactating women should consult a doctor before using any product.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.

Not intended for use by persons under the age of 18.

Formulation Notes

Contains no: Chemical Fillers or Binders, Artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

From a GMP Facility

Piper methysticum

Supports stress relief

Additional Information

Store in a dry place and avoid excessive heat.

Metadata

Product Details

DSLD Entry Date2025-09-25
Product TypeBotanical
FormCapsule
DSLD ID338799
Data Updated2026-04-11
Research

Research Evidence

19
Research Sources
48
Avg Quality
8
Rct
5
Systematic Review
4
Meta Analysis
2
Clinical Trial
B Kava extract for treating anxiety
Meta Analysis The Cochrane database of systematic reviews 2003 PubMed
B Kava for Generalized Anxiety Disorder: A Review of Current Evidence
Meta Analysis Journal of alternative and complementary medicine (New York, N.Y.) 2018 PubMed DOI
B Kava extract for treating anxiety
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Kava extract for treating anxiety
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The effectiveness and safety of Kava Kava for treating anxiety symptoms: A systematic review and analysis of randomized clinical trials
Systematic Review Complementary therapies in clinical practice 2018 PubMed DOI
C Kava for generalised anxiety disorder: A 16-week double-blind, randomised, placebo-controlled study
Rct The Australian and New Zealand journal of psychiatry 2020 PubMed DOI
C Kava and St. John's Wort: current evidence for use in mood and anxiety disorders
Systematic Review Journal of alternative and complementary medicine (New York, N.Y.) 2009 PubMed DOI
C Neuroimaging Insights: Kava's (Piper methysticum) Effect on Dorsal Anterior Cingulate Cortex GABA in Generalized Anxiety Disorder.
Rct Nutrients PubMed DOI
C The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava
Meta Analysis Annals of internal medicine 2002 PubMed
C Efficacy of kava extract for treating anxiety: systematic review and meta-analysis
Meta Analysis Journal of clinical psychopharmacology 2000 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.